MNK inversely regulates TELO2 vs. DEPTOR to control mTORC1 signaling.
Publication
, Journal Article
Brown, MC; Gromeier, M
Published in: Mol Cell Oncol
2017
mTORC1 is the major homeostatic nutrient sensor for the cell. As such, it is integrated into diverse signaling networks and co-factor interactions that determine its activity. Our recent work implicates the mTORC1 co-factor and PI3K-related Kinase (PIKK) stabilizer, TELO2, in regulating mTORC1 activity in a MAPK-Interacting Kinase (MNK) responsive manner during mitogenic stimulation of cancer cells and T cell activation.
Duke Scholars
Published In
Mol Cell Oncol
DOI
ISSN
2372-3556
Publication Date
2017
Volume
4
Issue
3
Start / End Page
e1306010
Location
United States
Related Subject Headings
- 3211 Oncology and carcinogenesis
- 3205 Medical biochemistry and metabolomics
Citation
APA
Chicago
ICMJE
MLA
NLM
Brown, M. C., & Gromeier, M. (2017). MNK inversely regulates TELO2 vs. DEPTOR to control mTORC1 signaling. Mol Cell Oncol, 4(3), e1306010. https://doi.org/10.1080/23723556.2017.1306010
Brown, Michael C., and Matthias Gromeier. “MNK inversely regulates TELO2 vs. DEPTOR to control mTORC1 signaling.” Mol Cell Oncol 4, no. 3 (2017): e1306010. https://doi.org/10.1080/23723556.2017.1306010.
Brown MC, Gromeier M. MNK inversely regulates TELO2 vs. DEPTOR to control mTORC1 signaling. Mol Cell Oncol. 2017;4(3):e1306010.
Brown, Michael C., and Matthias Gromeier. “MNK inversely regulates TELO2 vs. DEPTOR to control mTORC1 signaling.” Mol Cell Oncol, vol. 4, no. 3, 2017, p. e1306010. Pubmed, doi:10.1080/23723556.2017.1306010.
Brown MC, Gromeier M. MNK inversely regulates TELO2 vs. DEPTOR to control mTORC1 signaling. Mol Cell Oncol. 2017;4(3):e1306010.
Published In
Mol Cell Oncol
DOI
ISSN
2372-3556
Publication Date
2017
Volume
4
Issue
3
Start / End Page
e1306010
Location
United States
Related Subject Headings
- 3211 Oncology and carcinogenesis
- 3205 Medical biochemistry and metabolomics