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Contemporary Strategies and Barriers to Transplantation Tolerance.

Publication ,  Journal Article
Ezekian, B; Schroder, PM; Freischlag, K; Yoon, J; Kwun, J; Knechtle, SJ
Published in: Transplantation
August 2018

The purpose of this review is to discuss immunologic tolerance as it applies to solid organ transplantation and to identify barriers that hinder the achievement of this long-term goal. First, the definition of tolerance and an introduction of mechanisms by which tolerance exists or can be achieved will be discussed. Next, a review of contemporary attempts at achieving transplant tolerance will be described. Finally, a discussion of the humoral barriers to transplantation tolerance and potential ways to overcome these barriers will be presented.

Duke Scholars

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Published In

Transplantation

DOI

EISSN

1534-6080

Publication Date

August 2018

Volume

102

Issue

8

Start / End Page

1213 / 1222

Location

United States

Related Subject Headings

  • Transplantation Tolerance
  • Thymus Gland
  • T-Lymphocytes, Regulatory
  • Surgery
  • Organ Transplantation
  • Mesenchymal Stem Cells
  • Macrophages
  • Immunosuppression Therapy
  • Humans
  • Graft Rejection
 

Citation

APA
Chicago
ICMJE
MLA
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Ezekian, B., Schroder, P. M., Freischlag, K., Yoon, J., Kwun, J., & Knechtle, S. J. (2018). Contemporary Strategies and Barriers to Transplantation Tolerance. Transplantation, 102(8), 1213–1222. https://doi.org/10.1097/TP.0000000000002242
Ezekian, Brian, Paul M. Schroder, Kyle Freischlag, Janghoon Yoon, Jean Kwun, and Stuart J. Knechtle. “Contemporary Strategies and Barriers to Transplantation Tolerance.Transplantation 102, no. 8 (August 2018): 1213–22. https://doi.org/10.1097/TP.0000000000002242.
Ezekian B, Schroder PM, Freischlag K, Yoon J, Kwun J, Knechtle SJ. Contemporary Strategies and Barriers to Transplantation Tolerance. Transplantation. 2018 Aug;102(8):1213–22.
Ezekian, Brian, et al. “Contemporary Strategies and Barriers to Transplantation Tolerance.Transplantation, vol. 102, no. 8, Aug. 2018, pp. 1213–22. Pubmed, doi:10.1097/TP.0000000000002242.
Ezekian B, Schroder PM, Freischlag K, Yoon J, Kwun J, Knechtle SJ. Contemporary Strategies and Barriers to Transplantation Tolerance. Transplantation. 2018 Aug;102(8):1213–1222.

Published In

Transplantation

DOI

EISSN

1534-6080

Publication Date

August 2018

Volume

102

Issue

8

Start / End Page

1213 / 1222

Location

United States

Related Subject Headings

  • Transplantation Tolerance
  • Thymus Gland
  • T-Lymphocytes, Regulatory
  • Surgery
  • Organ Transplantation
  • Mesenchymal Stem Cells
  • Macrophages
  • Immunosuppression Therapy
  • Humans
  • Graft Rejection