Cellular brain ischemia and stroke: Neuroprotection, metabolism, and new strategies for brain recovery

Each year 4.6 million people die from stroke worldwide and 75% of these cases occur in industrialized countries.1 In the U.S., stroke is the third leading cause of mortality, with 4.7 million survivors, 15 to 30% of whom are left with permanent disabilities and 20% of whom require long-term institutional care.2 Significant social, financial, and personal problems occur as a result of these disabilities.3 Stroke is a generic term, encompassing a wide variety of vascular diseases affecting the nervous system. Treatment of these diverse disease processes necessarily involves several different approaches.

Duke Scholars

Author Larry Bruce Goldstein Neurology, Stroke and Vascular Neurology

Author Dennis Alan Turner Neurosurgery