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Associations between neuropsychiatric and health status outcomes in individuals with probable mTBI.

Publication ,  Journal Article
Bomyea, J; Flashman, LA; Zafonte, R; Andaluz, N; Coimbra, R; George, MS; Grant, GA; Marx, CE; McAllister, TW; Shutter, L; Lang, AJ; Stein, MB
Published in: Psychiatry Res
February 2019

Mild traumatic brain injury (mTBI) is a common occurrence, and may impact distal outcomes in a subgroup of individuals. Improved characterization of health outcomes and identification of factors associated with poor outcomes is needed to better understand the impact of mTBI, particularly in those with co-occurring posttraumatic stress disorder (PTSD). Participants in a data repository of the Injury and Traumatic Stress (INTRuST) Clinical Consortium (n = 625) completed functional disability [FD] and health-related quality of life [HRQOL] questionnaires, and a subset completed a neuropsychological assessment. FD and HRQOL were compared among participants with probable mTBI (mTBI), probable mTBI with PTSD (mTBI/PTSD), and health comparison participants (HC). Associations between symptoms, neuropsychological performance, and health outcomes were examined in those with probable mTBI with and without PTSD (n = 316). Individuals in the mTBI/PTSD group endorsed poorer health outcomes than those in the mTBI group, who endorsed poorer outcomes than those in the HC group. Individuals in either mTBI group performed worse than those in the HC on verbal learning and memory and psychomotor speed. Health outcomes were correlated with mental health and postconcussive symptoms, as well as neuropsychological variables. mTBI may adversely impact self-reported health, with the greatest effect observed in individuals with co-occurring mTBI/PTSD.

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Published In

Psychiatry Res

DOI

EISSN

1872-7123

Publication Date

February 2019

Volume

272

Start / End Page

531 / 539

Location

Ireland

Related Subject Headings

  • Young Adult
  • Surveys and Questionnaires
  • Stress Disorders, Post-Traumatic
  • Self Report
  • Quality of Life
  • Psychiatry
  • Post-Concussion Syndrome
  • Neuropsychological Tests
  • Middle Aged
  • Memory
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Bomyea, J., Flashman, L. A., Zafonte, R., Andaluz, N., Coimbra, R., George, M. S., … Stein, M. B. (2019). Associations between neuropsychiatric and health status outcomes in individuals with probable mTBI. Psychiatry Res, 272, 531–539. https://doi.org/10.1016/j.psychres.2018.12.021
Bomyea, Jessica, Laura A. Flashman, Ross Zafonte, Norberto Andaluz, Raul Coimbra, Mark S. George, Gerald A. Grant, et al. “Associations between neuropsychiatric and health status outcomes in individuals with probable mTBI.Psychiatry Res 272 (February 2019): 531–39. https://doi.org/10.1016/j.psychres.2018.12.021.
Bomyea J, Flashman LA, Zafonte R, Andaluz N, Coimbra R, George MS, et al. Associations between neuropsychiatric and health status outcomes in individuals with probable mTBI. Psychiatry Res. 2019 Feb;272:531–9.
Bomyea, Jessica, et al. “Associations between neuropsychiatric and health status outcomes in individuals with probable mTBI.Psychiatry Res, vol. 272, Feb. 2019, pp. 531–39. Pubmed, doi:10.1016/j.psychres.2018.12.021.
Bomyea J, Flashman LA, Zafonte R, Andaluz N, Coimbra R, George MS, Grant GA, Marx CE, McAllister TW, Shutter L, Lang AJ, Stein MB. Associations between neuropsychiatric and health status outcomes in individuals with probable mTBI. Psychiatry Res. 2019 Feb;272:531–539.
Journal cover image

Published In

Psychiatry Res

DOI

EISSN

1872-7123

Publication Date

February 2019

Volume

272

Start / End Page

531 / 539

Location

Ireland

Related Subject Headings

  • Young Adult
  • Surveys and Questionnaires
  • Stress Disorders, Post-Traumatic
  • Self Report
  • Quality of Life
  • Psychiatry
  • Post-Concussion Syndrome
  • Neuropsychological Tests
  • Middle Aged
  • Memory