Skip to main content

Health-related quality of life loss associated with first-time stroke.

Publication ,  Journal Article
Yeoh, YS; Koh, GC-H; Tan, CS; Tu, TM; Singh, R; Chang, HM; De Silva, DA; Ng, YS; Ang, YH; Yap, P; Chew, E; Merchant, RA; Yeo, TT; Chou, N ...
Published in: PLoS One
2019

OBJECTIVES: This study aimed to quantify health-related quality of life (HRQoL) loss associated with first episode of stroke by comparing patient-reported HRQoL before and after stroke onset. The impact of stroke in local population was also evaluated by comparing the pre- and post-stroke HRQoL with that of the general population. METHODS: The HRQoL of stroke survivors was assessed with the EQ-5D-3L index score at recruitment, for recalled pre-stroke HRQoL, and at 3 and 12 month post-stroke. Change in HRQoL from pre-stroke to 3 and 12 month was self-reported by 285 and 238 patients, respectively. Mean EQ index score at each time point (baseline: 464 patients; 3 month post-stroke: 306 patients; 12 month post-stroke: 258 patients) was compared with published population norms for EQ-5D-3L. RESULTS: There was a significant decrease in HRQoL at 3 (0.25) and 12 month (0.09) post-stroke when compared to the retrospectively recalled patients' mean pre-stroke HRQoL level (0.87). The reduction at 3 month was associated with the reduction in all EQ-5D-3L health dimensions; reductions remaining at 12 month were limited to dimensions of mobility, self-care, usual activities, and anxiety/depression. Stroke patients had a lower mean EQ index than the general population by 0.07 points pre-stroke (0.87 vs. 0.94), 0.33 points at 3 month (0.61 vs. 0.94) and 0.18 points at 12 month (0.76 vs. 0.94) post-stroke. CONCLUSIONS: Stroke has a substantial impact on HRQoL in Singapore, especially in the first three months post-stroke. Compared to the general population, stroke survivors have lower HRQoL even before stroke onset. This pre-stroke deficit in HRQoL should be taken into account when quantifying health burden of stroke or setting goals for stroke rehabilitation.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

PLoS One

DOI

EISSN

1932-6203

Publication Date

2019

Volume

14

Issue

1

Start / End Page

e0211493

Location

United States

Related Subject Headings

  • Survivors
  • Surveys and Questionnaires
  • Stroke Rehabilitation
  • Stroke
  • Self Care
  • Retrospective Studies
  • Quality of Life
  • Outcome Assessment, Health Care
  • Middle Aged
  • Male
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Yeoh, Y. S., Koh, G.-H., Tan, C. S., Tu, T. M., Singh, R., Chang, H. M., … Luo, N. (2019). Health-related quality of life loss associated with first-time stroke. PLoS One, 14(1), e0211493. https://doi.org/10.1371/journal.pone.0211493
Yeoh, Yen Shing, Gerald Choon-Huat Koh, Chuen Seng Tan, Tian Ming Tu, Rajinder Singh, Hui Meng Chang, Deidre A. De Silva, et al. “Health-related quality of life loss associated with first-time stroke.PLoS One 14, no. 1 (2019): e0211493. https://doi.org/10.1371/journal.pone.0211493.
Yeoh YS, Koh GC-H, Tan CS, Tu TM, Singh R, Chang HM, et al. Health-related quality of life loss associated with first-time stroke. PLoS One. 2019;14(1):e0211493.
Yeoh, Yen Shing, et al. “Health-related quality of life loss associated with first-time stroke.PLoS One, vol. 14, no. 1, 2019, p. e0211493. Pubmed, doi:10.1371/journal.pone.0211493.
Yeoh YS, Koh GC-H, Tan CS, Tu TM, Singh R, Chang HM, De Silva DA, Ng YS, Ang YH, Yap P, Chew E, Merchant RA, Yeo TT, Chou N, Venketasubramanian N, Lee KE, Young SH, Hoenig H, Matchar DB, Luo N. Health-related quality of life loss associated with first-time stroke. PLoS One. 2019;14(1):e0211493.

Published In

PLoS One

DOI

EISSN

1932-6203

Publication Date

2019

Volume

14

Issue

1

Start / End Page

e0211493

Location

United States

Related Subject Headings

  • Survivors
  • Surveys and Questionnaires
  • Stroke Rehabilitation
  • Stroke
  • Self Care
  • Retrospective Studies
  • Quality of Life
  • Outcome Assessment, Health Care
  • Middle Aged
  • Male