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Heart Failure Site-Based Research in the United States: Results of the Heart Failure Society of America Research Network Survey.

Publication ,  Journal Article
Psotka, MA; Ammon, SE; Fiuzat, M; Bozkurt, B; Chung, ES; Cole, RT; Greene, SJ; Kraus, D; Ky, B; McIlvennan, CK; Shah, P; Teerlink, JR ...
Published in: JACC Heart Fail
May 2019

OBJECTIVES: This study sought to determine clinician and scientist involvement in heart failure (HF) clinical research and to describe the challenges of conducting clinical trials in the United States. BACKGROUND: Improvements in the current capability, potential, and deficiencies of the HF clinical research infrastructure in the United States are needed in order to enhance efficiency and impact. METHODS: The Heart Failure Society of America (HFSA) distributed an electronic survey regarding HF clinical trial activity for the purpose of understanding the barriers that exist to conducting high-quality HF clinical research. RESULTS: Overall, 1,794 HFSA members were queried, and 434 members (24%) completed surveys, whereas a total of 7,589 individuals with interest in HF were queried, and 615 completed surveys. Of the respondents, 410 (67%) were actively engaged in HF research and 120 (20%) were interested in research. Most respondents, 270, were physicians (44%); 311 of the total (76% of the total and 80% of physicians) practiced in academic institutions; 333 respondents (81%) had served as principal investigators and 73 (18%) as site coordinators. Respondents active in clinical research usually participated in 1 to 5 trials and enrolled 1 to 20 patients annually. Institutional review board (IRB) approval typically required 3 months, and contract completion required 3 to 6 months per site. The greatest barriers to research were insufficient site budgets, delay in contracting, inability to find participants meeting trial entry criteria, and unavailability of qualified study coordinators. CONCLUSIONS: Many U.S. clinical research sites are constrained by budgetary, staffing, and contractual issues. The HFSA Research Network seeks to unify interested sites and deconstruct barriers to permit high-value HF research.

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Published In

JACC Heart Fail

DOI

EISSN

2213-1787

Publication Date

May 2019

Volume

7

Issue

5

Start / End Page

431 / 438

Location

United States

Related Subject Headings

  • United States
  • Time Factors
  • Surveys and Questionnaires
  • Societies, Medical
  • Research Support as Topic
  • Research Personnel
  • Physicians
  • Patient Selection
  • Nurses
  • Nurse Practitioners
 

Citation

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Psotka, M. A., Ammon, S. E., Fiuzat, M., Bozkurt, B., Chung, E. S., Cole, R. T., … O’Connor, C. M. (2019). Heart Failure Site-Based Research in the United States: Results of the Heart Failure Society of America Research Network Survey. JACC Heart Fail, 7(5), 431–438. https://doi.org/10.1016/j.jchf.2019.02.008
Psotka, Mitchell A., Susan E. Ammon, Mona Fiuzat, Biykem Bozkurt, Eugene S. Chung, Robert T. Cole, Stephen J. Greene, et al. “Heart Failure Site-Based Research in the United States: Results of the Heart Failure Society of America Research Network Survey.JACC Heart Fail 7, no. 5 (May 2019): 431–38. https://doi.org/10.1016/j.jchf.2019.02.008.
Psotka MA, Ammon SE, Fiuzat M, Bozkurt B, Chung ES, Cole RT, et al. Heart Failure Site-Based Research in the United States: Results of the Heart Failure Society of America Research Network Survey. JACC Heart Fail. 2019 May;7(5):431–8.
Psotka, Mitchell A., et al. “Heart Failure Site-Based Research in the United States: Results of the Heart Failure Society of America Research Network Survey.JACC Heart Fail, vol. 7, no. 5, May 2019, pp. 431–38. Pubmed, doi:10.1016/j.jchf.2019.02.008.
Psotka MA, Ammon SE, Fiuzat M, Bozkurt B, Chung ES, Cole RT, Greene SJ, Kraus D, Ky B, McIlvennan CK, Shah P, Teerlink JR, Walsh MN, Jessup M, O’Connor CM. Heart Failure Site-Based Research in the United States: Results of the Heart Failure Society of America Research Network Survey. JACC Heart Fail. 2019 May;7(5):431–438.
Journal cover image

Published In

JACC Heart Fail

DOI

EISSN

2213-1787

Publication Date

May 2019

Volume

7

Issue

5

Start / End Page

431 / 438

Location

United States

Related Subject Headings

  • United States
  • Time Factors
  • Surveys and Questionnaires
  • Societies, Medical
  • Research Support as Topic
  • Research Personnel
  • Physicians
  • Patient Selection
  • Nurses
  • Nurse Practitioners