Computerized cognitive training in pediatric sickle cell disease: A randomized controlled pilot study.
Objective: The current study assessed the feasibility of a computerized cognitive intervention, Cogmed, in a sample of youth with SCD (ages 8–16 years). If deemed feasible, the secondary aim of the study was to evaluate preliminary efficacy. Methods: Youth with SCD were randomized to a waitlist control or the Cogmed program. Data pertaining to cognitive functioning, psychosocial functioning, and disease characteristics were obtained from participants pre- and postintervention. In addition, data regarding participant interest, consent rate, and intervention compliance were tracked. Results: Eighteen participants (M = 12.2 years old) enrolled in this study. Results indicate that the majority of prospective families approached about the intervention (82%) expressed interest in participating in the study, although less than 25% of interested participants enrolled. Three of 18 consenting participants completed the intervention. Cognitive, medical, and psychosocial factors related to feasibility and compliance were identified. Conclusions: Taken together, the results of this study suggest that there is a high degree of interest for this type of intervention but poor feasibility in practice. Implications and future directions are discussed. (PsycInfo Database Record (c) 2020 APA, all rights reserved)Implications for Impact Statement: Children with sickle cell disease (SCD) have a high risk of neurocognitive impairment, for which there are no interventions supported by research. While the computerized, game-like treatment “Cogmed” has been successfully used with other groups, the current study demonstrated very limited tolerability in youth with SCD. Thus, additional efforts are needed to innovate new cognitive therapies for this unique and in need population of children. (PsycInfo Database Record (c) 2020 APA, all rights reserved)
