Skip to main content
construction release_alert
Scholars@Duke will be undergoing maintenance April 11-15. Some features may be unavailable during this time.
cancel
Journal cover image

Impact of interruptions in radiofrequency energy delivery on lesion characteristics.

Publication ,  Journal Article
Friedman, DJ; Overmann, JA; Fish, JM; Gaeta, SA; Tranter, JH; Thao, R; Piccini, JP
Published in: Heart Rhythm
August 2020

BACKGROUND: During catheter ablation, delivery of radiofrequency (RF) energy to a target site is sometimes interrupted by catheter instability and clinical factors. The impact of interruption of RF delivery on lesion characteristics has not been characterized. OBJECTIVE: The purpose of this study was to determine the impact of interruption of RF application on lesion size. METHODS: Forty-two RF ablation lesions (21 left ventricle, 21 right ventricle) were created in the ventricles of 6 swine using power control mode (30 W; target contact force 15g) with 1 of 3 conditions: 15-second ablation (15s), 30-second ablation (30s), or two 15-second ablations (15s×2) at the same site separated by a 2-minute pause. RESULTS: Lesion volume was significantly larger for 30s lesions (501 ± 146 mm3) compared to both 15s×2 (314 ± 98 mm3) and 15s (242 ± 104 mm3) lesions (P <.001 for both pairwise comparisons). Compared to 15s lesions, lesion volume was numerically greater for 15s×2 lesions, but this did not reach statistical significance (P = .087). Differences in lesion volume between 30s and 15s×2 lesions were driven mainly by differences in lesion width (10.7 ± 1.1 mm vs 9.1 ± 1.7 mm; P = .04) rather than depth (9 ± 1.2 mm vs 8.4 ± 1.2 mm; P = .29). There were no differences in mean contact force by group. There was no difference in total force-time integral for the 30s and 15s×2 lesion groups [median 444 (interquartile range 312) g∙s vs 380 (164) g∙s; P = 1]. CONCLUSION: Compared to lesions resulting from continuous RF ablation, lesions resulting from interrupted ablation have a smaller overall lesion volume, predominantly due to smaller lesion width. These data suggest that if disruption in energy delivery occurs, lesions may need closer spacing to avoid gaps.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Heart Rhythm

DOI

EISSN

1556-3871

Publication Date

August 2020

Volume

17

Issue

8

Start / End Page

1354 / 1359

Location

United States

Related Subject Headings

  • Swine
  • Male
  • Heart Ventricles
  • Disease Models, Animal
  • Catheter Ablation
  • Cardiovascular System & Hematology
  • Arrhythmias, Cardiac
  • Animals
  • 3201 Cardiovascular medicine and haematology
  • 1102 Cardiorespiratory Medicine and Haematology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Friedman, D. J., Overmann, J. A., Fish, J. M., Gaeta, S. A., Tranter, J. H., Thao, R., & Piccini, J. P. (2020). Impact of interruptions in radiofrequency energy delivery on lesion characteristics. Heart Rhythm, 17(8), 1354–1359. https://doi.org/10.1016/j.hrthm.2020.03.008
Friedman, Daniel J., Jed A. Overmann, Jeffrey M. Fish, Stephen A. Gaeta, John H. Tranter, Riki Thao, and Jonathan P. Piccini. “Impact of interruptions in radiofrequency energy delivery on lesion characteristics.Heart Rhythm 17, no. 8 (August 2020): 1354–59. https://doi.org/10.1016/j.hrthm.2020.03.008.
Friedman DJ, Overmann JA, Fish JM, Gaeta SA, Tranter JH, Thao R, et al. Impact of interruptions in radiofrequency energy delivery on lesion characteristics. Heart Rhythm. 2020 Aug;17(8):1354–9.
Friedman, Daniel J., et al. “Impact of interruptions in radiofrequency energy delivery on lesion characteristics.Heart Rhythm, vol. 17, no. 8, Aug. 2020, pp. 1354–59. Pubmed, doi:10.1016/j.hrthm.2020.03.008.
Friedman DJ, Overmann JA, Fish JM, Gaeta SA, Tranter JH, Thao R, Piccini JP. Impact of interruptions in radiofrequency energy delivery on lesion characteristics. Heart Rhythm. 2020 Aug;17(8):1354–1359.
Journal cover image

Published In

Heart Rhythm

DOI

EISSN

1556-3871

Publication Date

August 2020

Volume

17

Issue

8

Start / End Page

1354 / 1359

Location

United States

Related Subject Headings

  • Swine
  • Male
  • Heart Ventricles
  • Disease Models, Animal
  • Catheter Ablation
  • Cardiovascular System & Hematology
  • Arrhythmias, Cardiac
  • Animals
  • 3201 Cardiovascular medicine and haematology
  • 1102 Cardiorespiratory Medicine and Haematology