Controversies of renin-angiotensin system inhibition during the COVID-19 pandemic.
Publication
, Journal Article
South, AM; Tomlinson, L; Edmonston, D; Hiremath, S; Sparks, MA
Published in: Nat Rev Nephrol
June 2020
The current COVID-19 pandemic is associated with unprecedented morbidity and mortality. Early reports suggested an association between disease severity and hypertension but did not account for sources of confounding. However, the responsible virus — SARS-CoV-2 — gains entry to host cells via angiotensin-converting enzyme 2 (ACE2), highlighting the need to understand the relationship between the virus and the renin–angiotensin system (RAS) and how this might be affected by RAS inhibitors.
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Published In
Nat Rev Nephrol
DOI
EISSN
1759-507X
Publication Date
June 2020
Volume
16
Issue
6
Start / End Page
305 / 307
Location
England
Related Subject Headings
- Virus Internalization
- Urology & Nephrology
- SARS-CoV-2
- Renin-Angiotensin System
- Pneumonia, Viral
- Peptidyl-Dipeptidase A
- Pandemics
- Humans
- Enzyme Inhibitors
- Coronavirus Infections
Citation
APA
Chicago
ICMJE
MLA
NLM
South, A. M., Tomlinson, L., Edmonston, D., Hiremath, S., & Sparks, M. A. (2020). Controversies of renin-angiotensin system inhibition during the COVID-19 pandemic. Nat Rev Nephrol, 16(6), 305–307. https://doi.org/10.1038/s41581-020-0279-4
South, Andrew M., Laurie Tomlinson, Daniel Edmonston, Swapnil Hiremath, and Matthew A. Sparks. “Controversies of renin-angiotensin system inhibition during the COVID-19 pandemic.” Nat Rev Nephrol 16, no. 6 (June 2020): 305–7. https://doi.org/10.1038/s41581-020-0279-4.
South AM, Tomlinson L, Edmonston D, Hiremath S, Sparks MA. Controversies of renin-angiotensin system inhibition during the COVID-19 pandemic. Nat Rev Nephrol. 2020 Jun;16(6):305–7.
South, Andrew M., et al. “Controversies of renin-angiotensin system inhibition during the COVID-19 pandemic.” Nat Rev Nephrol, vol. 16, no. 6, June 2020, pp. 305–07. Pubmed, doi:10.1038/s41581-020-0279-4.
South AM, Tomlinson L, Edmonston D, Hiremath S, Sparks MA. Controversies of renin-angiotensin system inhibition during the COVID-19 pandemic. Nat Rev Nephrol. 2020 Jun;16(6):305–307.
Published In
Nat Rev Nephrol
DOI
EISSN
1759-507X
Publication Date
June 2020
Volume
16
Issue
6
Start / End Page
305 / 307
Location
England
Related Subject Headings
- Virus Internalization
- Urology & Nephrology
- SARS-CoV-2
- Renin-Angiotensin System
- Pneumonia, Viral
- Peptidyl-Dipeptidase A
- Pandemics
- Humans
- Enzyme Inhibitors
- Coronavirus Infections