Neuromodulation therapy for atrial fibrillation.
Publication
, Journal Article
Karatela, MF; Fudim, M; Mathew, JP; Piccini, JP
Published in: Heart Rhythm
January 2023
Atrial fibrillation has a multifactorial pathophysiology influenced by cardiac autonomic innervation. Both sympathetic and parasympathetic influences are profibrillatory. Innovative therapies targeting the neurocardiac axis include catheter ablation or pharmacologic suppression of ganglionated plexi, renal sympathetic denervation, low-level vagal stimulation, and stellate ganglion blockade. To date, these therapies have variable efficacy. As our understanding of atrial fibrillation and the cardiac nervous system expands, our approach to therapeutic neuromodulation will continue evolving for the benefit of those with AF.
Duke Scholars
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Published In
Heart Rhythm
DOI
EISSN
1556-3871
Publication Date
January 2023
Volume
20
Issue
1
Start / End Page
100 / 111
Location
United States
Related Subject Headings
- Sympathectomy
- Humans
- Heart Rate
- Heart
- Catheter Ablation
- Cardiovascular System & Hematology
- Autonomic Nervous System
- Atrial Fibrillation
- 3201 Cardiovascular medicine and haematology
- 1102 Cardiorespiratory Medicine and Haematology
Citation
APA
Chicago
ICMJE
MLA
NLM
Karatela, M. F., Fudim, M., Mathew, J. P., & Piccini, J. P. (2023). Neuromodulation therapy for atrial fibrillation. Heart Rhythm, 20(1), 100–111. https://doi.org/10.1016/j.hrthm.2022.08.011
Karatela, Maham F., Marat Fudim, Joseph P. Mathew, and Jonathan P. Piccini. “Neuromodulation therapy for atrial fibrillation.” Heart Rhythm 20, no. 1 (January 2023): 100–111. https://doi.org/10.1016/j.hrthm.2022.08.011.
Karatela MF, Fudim M, Mathew JP, Piccini JP. Neuromodulation therapy for atrial fibrillation. Heart Rhythm. 2023 Jan;20(1):100–11.
Karatela, Maham F., et al. “Neuromodulation therapy for atrial fibrillation.” Heart Rhythm, vol. 20, no. 1, Jan. 2023, pp. 100–11. Pubmed, doi:10.1016/j.hrthm.2022.08.011.
Karatela MF, Fudim M, Mathew JP, Piccini JP. Neuromodulation therapy for atrial fibrillation. Heart Rhythm. 2023 Jan;20(1):100–111.
Published In
Heart Rhythm
DOI
EISSN
1556-3871
Publication Date
January 2023
Volume
20
Issue
1
Start / End Page
100 / 111
Location
United States
Related Subject Headings
- Sympathectomy
- Humans
- Heart Rate
- Heart
- Catheter Ablation
- Cardiovascular System & Hematology
- Autonomic Nervous System
- Atrial Fibrillation
- 3201 Cardiovascular medicine and haematology
- 1102 Cardiorespiratory Medicine and Haematology