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Dosimetric variation in preoperative partial breast radiosurgery assessed by deformable image registrations.

Publication ,  Journal Article
Yoo, S; Blitzblau, R; McDuff, S; Yin, F-F; Cui, Y
Published in: J Radiosurg SBRT
2022

OBJECTIVE: To assess dosimetric variation caused by breast deformation in breast radiosurgery based on deformable image registration. METHODS: This study included 30 patients who were treated in the prone position for preoperative partial breast radiosurgery. The biopsy clip in CBCT was aligned to the one from the planning CT. Deformable image registration (DIR) was performed to deform the planning CT into the CBCT, focusing on the breast shape. The treated plan (PTx) was recalculated based on the deformed CT. Thus, PTx represented the actual treatment delivered to the patient and was compared to the original plan (POrg). RESULTS: The mean differences of target volumes covered by 95% and 100% of the prescribed dose between POrg and PTx were less than 0.5%. The mean differences ± standard division for skin maximum dose (Dmax), dose to 1cc (D1cc) and D10cc were 0.3 ± 0.7 Gy, 0.3 ± 0.6 Gy and 0.6 ± 0.6Gy between POrg and PTx, respectively. CONCLUSION: The treated plan was accurately recalculated based on the deformed CT. Despite slight variance in breast deformation, the dosimetric variation was very small, ensuring that adequate target coverage and skin dose were maintained during treatment as planned originally.

Duke Scholars

Published In

J Radiosurg SBRT

EISSN

2156-4647

Publication Date

2022

Volume

8

Issue

3

Start / End Page

227 / 235

Location

United States
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Yoo, S., Blitzblau, R., McDuff, S., Yin, F.-F., & Cui, Y. (2022). Dosimetric variation in preoperative partial breast radiosurgery assessed by deformable image registrations. J Radiosurg SBRT, 8(3), 227–235.
Yoo, Sua, Rachel Blitzblau, Susan McDuff, Fang-Fang Yin, and Yunfeng Cui. “Dosimetric variation in preoperative partial breast radiosurgery assessed by deformable image registrations.J Radiosurg SBRT 8, no. 3 (2022): 227–35.
Yoo S, Blitzblau R, McDuff S, Yin F-F, Cui Y. Dosimetric variation in preoperative partial breast radiosurgery assessed by deformable image registrations. J Radiosurg SBRT. 2022;8(3):227–35.
Yoo, Sua, et al. “Dosimetric variation in preoperative partial breast radiosurgery assessed by deformable image registrations.J Radiosurg SBRT, vol. 8, no. 3, 2022, pp. 227–35.
Yoo S, Blitzblau R, McDuff S, Yin F-F, Cui Y. Dosimetric variation in preoperative partial breast radiosurgery assessed by deformable image registrations. J Radiosurg SBRT. 2022;8(3):227–235.

Published In

J Radiosurg SBRT

EISSN

2156-4647

Publication Date

2022

Volume

8

Issue

3

Start / End Page

227 / 235

Location

United States