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ALSUntangled #70: caffeine.

Publication ,  Journal Article
Hatch, J; Barkhaus, P; Barnes, B; Beauchamp, M; Benatar, M; Bertorini, T; Bowser, R; Bromberg, M; Brown, A; Mascias Cadavid, J; Carter, GT ...
Published in: Amyotroph Lateral Scler Frontotemporal Degener
June 8, 2023

ALSUntangled reviews alternative and off-label treatments for people living with amyotrophic lateral sclerosis (PALS). Here, we review caffeine which has plausible mechanisms for slowing ALS progression. However, pre-clinical studies are contradictory, and a large case series showed no relationship between caffeine intake and ALS progression rate. While low doses of caffeine are safe and inexpensive, higher doses can cause serious side effects. At this time, we cannot endorse caffeine as a treatment to slow ALS progression.

Duke Scholars

Published In

Amyotroph Lateral Scler Frontotemporal Degener

DOI

EISSN

2167-9223

Publication Date

June 8, 2023

Start / End Page

1 / 5

Location

England

Related Subject Headings

  • 3209 Neurosciences
  • 1109 Neurosciences
  • 1103 Clinical Sciences
 

Citation

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ICMJE
MLA
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Hatch, J., Barkhaus, P., Barnes, B., Beauchamp, M., Benatar, M., Bertorini, T., … Bedlack, R. (2023). ALSUntangled #70: caffeine. Amyotroph Lateral Scler Frontotemporal Degener, 1–5. https://doi.org/10.1080/21678421.2023.2220742
Hatch, Jessica, Paul Barkhaus, Benjamin Barnes, Morgan Beauchamp, Michael Benatar, Tulio Bertorini, Robert Bowser, et al. “ALSUntangled #70: caffeine.Amyotroph Lateral Scler Frontotemporal Degener, June 8, 2023, 1–5. https://doi.org/10.1080/21678421.2023.2220742.
Hatch J, Barkhaus P, Barnes B, Beauchamp M, Benatar M, Bertorini T, et al. ALSUntangled #70: caffeine. Amyotroph Lateral Scler Frontotemporal Degener. 2023 Jun 8;1–5.
Hatch, Jessica, et al. “ALSUntangled #70: caffeine.Amyotroph Lateral Scler Frontotemporal Degener, June 2023, pp. 1–5. Pubmed, doi:10.1080/21678421.2023.2220742.
Hatch J, Barkhaus P, Barnes B, Beauchamp M, Benatar M, Bertorini T, Bowser R, Bromberg M, Brown A, Mascias Cadavid J, Carter GT, Cole N, Crayle J, Dimachkie M, Ennist D, Feldman E, Fullam T, Heiman-Patterson T, Jhooty S, Levine T, Li X, Lund I, Mallon E, Maragakis N, McDermott C, Pattee G, Pierce K, Ratner D, Staats K, Wicks P, Wiedau M, Bedlack R. ALSUntangled #70: caffeine. Amyotroph Lateral Scler Frontotemporal Degener. 2023 Jun 8;1–5.

Published In

Amyotroph Lateral Scler Frontotemporal Degener

DOI

EISSN

2167-9223

Publication Date

June 8, 2023

Start / End Page

1 / 5

Location

England

Related Subject Headings

  • 3209 Neurosciences
  • 1109 Neurosciences
  • 1103 Clinical Sciences