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The Association of Race and Ethnicity with Mortality in Pediatric Patients with Congenital Heart Disease: a Systematic Review.

Publication ,  Journal Article
Sooy-Mossey, M; Matsuura, M; Ezekian, JE; Williams, JL; Lee, GS; Wood, K; Dizon, S; Kaplan, SJ; Li, JS; Parente, V
Published in: J Racial Ethn Health Disparities
July 12, 2023

CONTEXT: Congenital heart disease (CHD) is a common condition with high morbidity and mortality and is subject to racial and ethnic health disparities. OBJECTIVE: To conduct a systematic review of the literature to identify differences in mortality in pediatric patients with CHD based on race and ethnicity. DATA SOURCES: Legacy PubMed (MEDLINE), Embase (Elsevier), and Scopus (Elsevier) STUDY SELECTION: English language articles conducted in the USA focused on mortality based on race and ethnicity in pediatric patients with CHD. DATA EXTRACTION: Two independent reviewers assessed studies for inclusion and performed data extraction and quality assessment. Data extraction included mortality based on patient race and ethnicity. RESULTS: There were 5094 articles identified. After de-duplication, 2971 were screened for title and abstract content, and 45 were selected for full-text assessment. Thirty studies were included for data extraction. An additional 8 articles were identified on reference review and included in data extraction for a total of 38 included studies. Eighteen of 26 studies showed increased risk of mortality in non-Hispanic Black patients. Results were heterogenous in Hispanic patients with eleven studies of 24 showing an increased risk of mortality. Results for other races demonstrated mixed outcomes. LIMITATIONS: Study cohorts and definitions of race and ethnicity were heterogenous, and there was some overlap in national datasets used. CONCLUSION: Overall, racial and ethnic disparities existed in the mortality of pediatric patients with CHD across a variety of mortality types, CHD lesions, and pediatric age ranges. Children of races and ethnicities other than non-Hispanic White generally had increased risk of mortality, with non-Hispanic Black children most consistently having the highest risk of mortality. Further investigation is needed into the underlying mechanisms of these disparities so interventions to reduce inequities in CHD outcomes can be implemented.

Duke Scholars

Published In

J Racial Ethn Health Disparities

DOI

EISSN

2196-8837

Publication Date

July 12, 2023

Location

Switzerland

Related Subject Headings

  • 4206 Public health
  • 1117 Public Health and Health Services
 

Citation

APA
Chicago
ICMJE
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Sooy-Mossey, M., Matsuura, M., Ezekian, J. E., Williams, J. L., Lee, G. S., Wood, K., … Parente, V. (2023). The Association of Race and Ethnicity with Mortality in Pediatric Patients with Congenital Heart Disease: a Systematic Review. J Racial Ethn Health Disparities. https://doi.org/10.1007/s40615-023-01687-2
Sooy-Mossey, Meredith, Mirai Matsuura, Jordan E. Ezekian, Jason L. Williams, Grace S. Lee, Kathleen Wood, Samantha Dizon, Samantha J. Kaplan, Jennifer S. Li, and Victoria Parente. “The Association of Race and Ethnicity with Mortality in Pediatric Patients with Congenital Heart Disease: a Systematic Review.J Racial Ethn Health Disparities, July 12, 2023. https://doi.org/10.1007/s40615-023-01687-2.
Sooy-Mossey M, Matsuura M, Ezekian JE, Williams JL, Lee GS, Wood K, et al. The Association of Race and Ethnicity with Mortality in Pediatric Patients with Congenital Heart Disease: a Systematic Review. J Racial Ethn Health Disparities. 2023 Jul 12;
Sooy-Mossey, Meredith, et al. “The Association of Race and Ethnicity with Mortality in Pediatric Patients with Congenital Heart Disease: a Systematic Review.J Racial Ethn Health Disparities, July 2023. Pubmed, doi:10.1007/s40615-023-01687-2.
Sooy-Mossey M, Matsuura M, Ezekian JE, Williams JL, Lee GS, Wood K, Dizon S, Kaplan SJ, Li JS, Parente V. The Association of Race and Ethnicity with Mortality in Pediatric Patients with Congenital Heart Disease: a Systematic Review. J Racial Ethn Health Disparities. 2023 Jul 12;
Journal cover image

Published In

J Racial Ethn Health Disparities

DOI

EISSN

2196-8837

Publication Date

July 12, 2023

Location

Switzerland

Related Subject Headings

  • 4206 Public health
  • 1117 Public Health and Health Services