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Improving Outcomes for Infants After Cardiopulmonary Bypass Surgery for Congenital Heart Disease: A Commentary on Recent Randomized Controlled Trials.

Publication ,  Journal Article
Schlapbach, LJ; Gibbons, KS; Butt, W; Kannankeril, PJ; Li, JS; Hill, KD ...
Published in: Pediatr Crit Care Med
November 1, 2023

The recent NITRIC and STRESS trials demonstrate opportunities to perform pragmatic large randomized trials in congenital heart disease. We discuss lessons learnt from these trials which can inform future trial design and conduct in the field of pediatric heart surgery.

Duke Scholars

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Published In

Pediatr Crit Care Med

DOI

ISSN

1529-7535

Publication Date

November 1, 2023

Volume

24

Issue

11

Start / End Page

961 / 965

Location

United States

Related Subject Headings

  • Randomized Controlled Trials as Topic
  • Pediatrics
  • Infant
  • Humans
  • Heart Defects, Congenital
  • Cardiopulmonary Bypass
  • Cardiac Surgical Procedures
  • 4205 Nursing
  • 3213 Paediatrics
  • 3202 Clinical sciences
 

Citation

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Schlapbach, L. J., Gibbons, K. S., Butt, W., Kannankeril, P. J., Li, J. S., Hill, K. D., & Nitric Oxide During Cardiopulmonary Bypass to Improve Recovery in Infants With Congenital Heart Defects Follow-Up (NITRIC) Study Group and the Steroids to Reduce Systemic Inflammation after Infant Heart Surgery (STRESS) Network Investigators. (2023). Improving Outcomes for Infants After Cardiopulmonary Bypass Surgery for Congenital Heart Disease: A Commentary on Recent Randomized Controlled Trials. Pediatr Crit Care Med, 24(11), 961–965. https://doi.org/10.1097/PCC.0000000000003344
Schlapbach, Luregn J., Kristen S. Gibbons, Warwick Butt, Prince J. Kannankeril, Jennifer S. Li, Kevin D. Hill, and Nitric Oxide During Cardiopulmonary Bypass to Improve Recovery in Infants With Congenital Heart Defects Follow-Up (NITRIC) Study Group and the Steroids to Reduce Systemic Inflammation after Infant Heart Surgery (STRESS) Network Investigators. “Improving Outcomes for Infants After Cardiopulmonary Bypass Surgery for Congenital Heart Disease: A Commentary on Recent Randomized Controlled Trials.Pediatr Crit Care Med 24, no. 11 (November 1, 2023): 961–65. https://doi.org/10.1097/PCC.0000000000003344.
Schlapbach LJ, Gibbons KS, Butt W, Kannankeril PJ, Li JS, Hill KD, et al. Improving Outcomes for Infants After Cardiopulmonary Bypass Surgery for Congenital Heart Disease: A Commentary on Recent Randomized Controlled Trials. Pediatr Crit Care Med. 2023 Nov 1;24(11):961–5.
Schlapbach, Luregn J., et al. “Improving Outcomes for Infants After Cardiopulmonary Bypass Surgery for Congenital Heart Disease: A Commentary on Recent Randomized Controlled Trials.Pediatr Crit Care Med, vol. 24, no. 11, Nov. 2023, pp. 961–65. Pubmed, doi:10.1097/PCC.0000000000003344.
Schlapbach LJ, Gibbons KS, Butt W, Kannankeril PJ, Li JS, Hill KD, Nitric Oxide During Cardiopulmonary Bypass to Improve Recovery in Infants With Congenital Heart Defects Follow-Up (NITRIC) Study Group and the Steroids to Reduce Systemic Inflammation after Infant Heart Surgery (STRESS) Network Investigators. Improving Outcomes for Infants After Cardiopulmonary Bypass Surgery for Congenital Heart Disease: A Commentary on Recent Randomized Controlled Trials. Pediatr Crit Care Med. 2023 Nov 1;24(11):961–965.

Published In

Pediatr Crit Care Med

DOI

ISSN

1529-7535

Publication Date

November 1, 2023

Volume

24

Issue

11

Start / End Page

961 / 965

Location

United States

Related Subject Headings

  • Randomized Controlled Trials as Topic
  • Pediatrics
  • Infant
  • Humans
  • Heart Defects, Congenital
  • Cardiopulmonary Bypass
  • Cardiac Surgical Procedures
  • 4205 Nursing
  • 3213 Paediatrics
  • 3202 Clinical sciences