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Mediator Kinase Inhibition Impedes Transcriptional Plasticity and Prevents Resistance to ERK/MAPK-Targeted Therapy in KRAS-Mutant Cancers.

Publication ,  Preprint
Wood, K; Nussbaum, D; Martz, C; Waters, A; Barrera, A; Rutter, J; Cerda-Smith, C; Stewart, A; Wu, C; Cakir, M; Levandowski, C; Kantrowitz, D ...
November 2, 2023

Duke Scholars

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Publication Date

November 2, 2023
 

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Wood, K., Nussbaum, D., Martz, C., Waters, A., Barrera, A., Rutter, J., … Taatjes, D. (2023). Mediator Kinase Inhibition Impedes Transcriptional Plasticity and Prevents Resistance to ERK/MAPK-Targeted Therapy in KRAS-Mutant Cancers. https://doi.org/10.21203/rs.3.rs-3511242/v1
Wood, Kris, Daniel Nussbaum, Colin Martz, Andrew Waters, Alejandro Barrera, Justine Rutter, Christian Cerda-Smith, et al. “Mediator Kinase Inhibition Impedes Transcriptional Plasticity and Prevents Resistance to ERK/MAPK-Targeted Therapy in KRAS-Mutant Cancers.,” November 2, 2023. https://doi.org/10.21203/rs.3.rs-3511242/v1.
Wood K, Nussbaum D, Martz C, Waters A, Barrera A, Rutter J, Cerda-Smith C, Stewart A, Wu C, Cakir M, Levandowski C, Kantrowitz D, McCall S, Pierobon M, Petricoin E, Smith J, Der C, Taatjes D. Mediator Kinase Inhibition Impedes Transcriptional Plasticity and Prevents Resistance to ERK/MAPK-Targeted Therapy in KRAS-Mutant Cancers. 2023.

DOI

Publication Date

November 2, 2023