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ALSUntangled #72: Insulin.

Publication ,  Journal Article
Brown, A; Armon, C; Barkhaus, P; Beauchamp, M; Bertorini, T; Bromberg, M; Cadavid, JM; Carter, GT; Crayle, J; Feldman, EL; Heiman-Patterson, T ...
Published in: Amyotroph Lateral Scler Frontotemporal Degener
May 2024

ALSUntangled reviews alternative and off-label treatments for people living with amyotrophic lateral sclerosis (PALS). Here we review insulin, which has at least one plausible mechanism for slowing ALS progression. However, pre-clinical studies are limited and there have been no trials in PALS yet. Insulin use in patients without a metabolic need may cause very serious and potentially lethal side effects. While further studies to evaluate potential benefits may be warranted, at this time we cannot endorse insulin treatment to slow ALS progression.

Duke Scholars

Published In

Amyotroph Lateral Scler Frontotemporal Degener

DOI

EISSN

2167-9223

Publication Date

May 2024

Volume

25

Issue

3-4

Start / End Page

416 / 419

Location

England

Related Subject Headings

  • Insulin
  • Humans
  • Amyotrophic Lateral Sclerosis
  • 3209 Neurosciences
  • 1109 Neurosciences
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Brown, A., Armon, C., Barkhaus, P., Beauchamp, M., Bertorini, T., Bromberg, M., … Bedlack, R. (2024). ALSUntangled #72: Insulin. Amyotroph Lateral Scler Frontotemporal Degener, 25(3–4), 416–419. https://doi.org/10.1080/21678421.2023.2288110
Brown, Andrew, Carmel Armon, Paul Barkhaus, Morgan Beauchamp, Tulio Bertorini, Mark Bromberg, Javier Mascias Cadavid, et al. “ALSUntangled #72: Insulin.Amyotroph Lateral Scler Frontotemporal Degener 25, no. 3–4 (May 2024): 416–19. https://doi.org/10.1080/21678421.2023.2288110.
Brown A, Armon C, Barkhaus P, Beauchamp M, Bertorini T, Bromberg M, et al. ALSUntangled #72: Insulin. Amyotroph Lateral Scler Frontotemporal Degener. 2024 May;25(3–4):416–9.
Brown, Andrew, et al. “ALSUntangled #72: Insulin.Amyotroph Lateral Scler Frontotemporal Degener, vol. 25, no. 3–4, May 2024, pp. 416–19. Pubmed, doi:10.1080/21678421.2023.2288110.
Brown A, Armon C, Barkhaus P, Beauchamp M, Bertorini T, Bromberg M, Cadavid JM, Carter GT, Crayle J, Feldman EL, Heiman-Patterson T, Jhooty S, Linares A, Li X, Mallon E, Mcdermott C, Mushannen T, Nathaniel G, Pattee G, Pierce K, Ratner D, Slactova L, Wicks P, Bedlack R. ALSUntangled #72: Insulin. Amyotroph Lateral Scler Frontotemporal Degener. 2024 May;25(3–4):416–419.

Published In

Amyotroph Lateral Scler Frontotemporal Degener

DOI

EISSN

2167-9223

Publication Date

May 2024

Volume

25

Issue

3-4

Start / End Page

416 / 419

Location

England

Related Subject Headings

  • Insulin
  • Humans
  • Amyotrophic Lateral Sclerosis
  • 3209 Neurosciences
  • 1109 Neurosciences
  • 1103 Clinical Sciences