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ALSUntangled #75: Portable neuromodulation stimulator therapy.

Publication ,  Journal Article
Officer, L; Armon, C; Barkhaus, P; Beauchamp, M; Benatar, M; Bertorini, T; Bowser, R; Bromberg, M; Brown, A; Carbunar, OM; Carter, GT; Li, X ...
Published in: Amyotroph Lateral Scler Frontotemporal Degener
April 26, 2024

Spurred by patient interest, ALSUntangled herein examines the potential of the Portable Neuromodulation Stimulator (PoNS™) in treating amyotrophic lateral sclerosis (ALS). The PoNS™ device, FDA-approved for the treatment of gait deficits in adult patients with multiple sclerosis, utilizes translingual neurostimulation to stimulate trigeminal and facial nerves via the tongue, aiming to induce neuroplastic changes. While there are early, promising data for PoNS treatment to improve gait and balance in multiple sclerosis, stroke, and traumatic brain injury, no pre-clinical or clinical studies have been performed in ALS. Although reasonably safe, high costs and prescription requirements will limit PoNS accessibility. At this time, due to the lack of ALS-relevant data, we cannot endorse the use of PoNS as an ALS treatment.

Duke Scholars

Published In

Amyotroph Lateral Scler Frontotemporal Degener

DOI

EISSN

2167-9223

Publication Date

April 26, 2024

Start / End Page

1 / 5

Location

England

Related Subject Headings

  • 3209 Neurosciences
  • 1109 Neurosciences
  • 1103 Clinical Sciences
 

Citation

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Officer, L., Armon, C., Barkhaus, P., Beauchamp, M., Benatar, M., Bertorini, T., … Bedlack, R. (2024). ALSUntangled #75: Portable neuromodulation stimulator therapy. Amyotroph Lateral Scler Frontotemporal Degener, 1–5. https://doi.org/10.1080/21678421.2024.2346825
Officer, Laurel, Carmel Armon, Paul Barkhaus, Morgan Beauchamp, Michael Benatar, Tulio Bertorini, Robert Bowser, et al. “ALSUntangled #75: Portable neuromodulation stimulator therapy.Amyotroph Lateral Scler Frontotemporal Degener, April 26, 2024, 1–5. https://doi.org/10.1080/21678421.2024.2346825.
Officer L, Armon C, Barkhaus P, Beauchamp M, Benatar M, Bertorini T, et al. ALSUntangled #75: Portable neuromodulation stimulator therapy. Amyotroph Lateral Scler Frontotemporal Degener. 2024 Apr 26;1–5.
Officer, Laurel, et al. “ALSUntangled #75: Portable neuromodulation stimulator therapy.Amyotroph Lateral Scler Frontotemporal Degener, Apr. 2024, pp. 1–5. Pubmed, doi:10.1080/21678421.2024.2346825.
Officer L, Armon C, Barkhaus P, Beauchamp M, Benatar M, Bertorini T, Bowser R, Bromberg M, Brown A, Carbunar OM, Carter GT, Crayle J, Denson K, Feldman E, Fullam T, Heiman-Patterson T, Jackson C, Jhooty S, Levinson D, Li X, Linares A, Mallon E, Mascias Cadavid J, Mcdermott C, Mushannen T, Ostrow L, Patel R, Pattee G, Ratner D, Sun Y, Sladky J, Wicks P, Bedlack R. ALSUntangled #75: Portable neuromodulation stimulator therapy. Amyotroph Lateral Scler Frontotemporal Degener. 2024 Apr 26;1–5.

Published In

Amyotroph Lateral Scler Frontotemporal Degener

DOI

EISSN

2167-9223

Publication Date

April 26, 2024

Start / End Page

1 / 5

Location

England

Related Subject Headings

  • 3209 Neurosciences
  • 1109 Neurosciences
  • 1103 Clinical Sciences