Development of next generation low-cost OCT towards improved point-of-care retinal imaging.
Publication
, Journal Article
Price, HB; Song, G; Wang, W; O'Kane, E; Lu, K; Jelly, E; Miller, DA; Wax, A
Published in: Biomedical optics express
February 2025
Low-cost optical coherence tomography (OCT) has shown promise in increasing access to noninvasive retinal imaging at the point of care, especially in low-resource environments. A next-generation low-cost OCT system is presented which improves performance over previous versions by employing balanced detection, improved spectrometer falloff, and an increased A-line rate of 40 kHz. An algorithm is presented for image display that uses a histogram matching procedure to improve contrast-to-noise ratio (CNR). Imaging performance is benchmarked with CNR analysis of retinal OCT images, demonstrating a CNR of 2.01 ± 0.39 (p < 0.0001) for macula images collected during a clinical trial, a significant improvement over previous low-cost OCT systems.
Duke Scholars
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Published In
Biomedical optics express
DOI
EISSN
2156-7085
ISSN
2156-7085
Publication Date
February 2025
Volume
16
Issue
2
Start / End Page
748 / 759
Related Subject Headings
- 5102 Atomic, molecular and optical physics
- 4003 Biomedical engineering
- 3212 Ophthalmology and optometry
- 0912 Materials Engineering
- 0205 Optical Physics
Citation
APA
Chicago
ICMJE
MLA
NLM
Price, H. B., Song, G., Wang, W., O’Kane, E., Lu, K., Jelly, E., … Wax, A. (2025). Development of next generation low-cost OCT towards improved point-of-care retinal imaging. Biomedical Optics Express, 16(2), 748–759. https://doi.org/10.1364/boe.551625
Price, Hillel B., Ge Song, Wan Wang, Erin O’Kane, Kechao Lu, Evan Jelly, David A. Miller, and Adam Wax. “Development of next generation low-cost OCT towards improved point-of-care retinal imaging.” Biomedical Optics Express 16, no. 2 (February 2025): 748–59. https://doi.org/10.1364/boe.551625.
Price HB, Song G, Wang W, O’Kane E, Lu K, Jelly E, et al. Development of next generation low-cost OCT towards improved point-of-care retinal imaging. Biomedical optics express. 2025 Feb;16(2):748–59.
Price, Hillel B., et al. “Development of next generation low-cost OCT towards improved point-of-care retinal imaging.” Biomedical Optics Express, vol. 16, no. 2, Feb. 2025, pp. 748–59. Epmc, doi:10.1364/boe.551625.
Price HB, Song G, Wang W, O’Kane E, Lu K, Jelly E, Miller DA, Wax A. Development of next generation low-cost OCT towards improved point-of-care retinal imaging. Biomedical optics express. 2025 Feb;16(2):748–759.
Published In
Biomedical optics express
DOI
EISSN
2156-7085
ISSN
2156-7085
Publication Date
February 2025
Volume
16
Issue
2
Start / End Page
748 / 759
Related Subject Headings
- 5102 Atomic, molecular and optical physics
- 4003 Biomedical engineering
- 3212 Ophthalmology and optometry
- 0912 Materials Engineering
- 0205 Optical Physics