Scholars@Duke publication: Are There Differences in Patient-Reported Outcomes Measurement Information System Scores After Total Knee and Total Ankle Arthroplasty in Matched Patients?

Are There Differences in Patient-Reported Outcomes Measurement Information System Scores After Total Knee and Total Ankle Arthroplasty in Matched Patients?

Publication , Journal Article

Leal, J; Holland, CT; Wu, CJ; Easley, ME; Nunley, JA; Ryan, SP; Bolognesi, MP; Wellman, SS; Jiranek, WA

Published in: J Arthroplasty

July 2025

BACKGROUND: The purpose of this study was to evaluate Patient-Reported Outcomes Measurement Information System (PROMIS) scores, a generic patient-reported outcome measure (PROM), as a tool to compare outcomes between total knee (TKA) and total ankle arthroplasty (TAA). METHODS: Patients who underwent TKA or TAA from January 1, 2019, to December 31, 2023, with at least 1 year of follow-up, were reviewed retrospectively. Upon application of the criteria, 2,418 TKAs and 500 TAAs were utilized for analysis. Demographics, PROMs, emergency department visits, readmissions, and revision surgeries were collected. Propensity score matching at a 3:1 ratio of TKA to TAA patients was then done, balancing age, sex, race, body mass index, and American Society of Anesthesiologists classification, which resulted in a final cohort of 1,256 TKAs and 470 TAAs. RESULTS: Preoperative PROMIS pain interference (PI) scores were similar between TKA and TAA, and both showed improvements by 6 weeks. Patients undergoing TAA, however, had a greater decrease in PI scores at 1 year (TKA: -10.0 [-15.0 to -5.0]) versus TAA: -11.0 [-17.0 to -6.0]; P = 0.044). Regarding PROMIS physical function (PF), preoperative scores were also similar for TKA and TAA patients. Additionally, patients in both groups had similar improvement in PF at 1 year; however, TKA patients had better PF at 6 weeks (TKA: 41.0 [36.0 to 46.0] versus TAA: 37.0 [33.0 to 41.0]; P < 0.001). Preoperative PROMIS depression scores were similar between groups and showed similar improvement after surgery. Joint-specific PROMs improved in each cohort, respectively. CONCLUSIONS: Both TKA and TAA showed improvement postoperatively in joint-specific PROMs, which concurrently resulted in PROMIS score improvement across all domains in both joints. This suggests that arthroplasties across different anatomic sites can be compared using generic PROMs. For TKA and TAA, similar improvements in PROMIS PI, PF, and depression were noted 1 year after surgery. LEVEL OF EVIDENCE: III.

Duke Scholars

Author William Arthur Jiranek Orthopaedic Surgery

Author Michael Paul Bolognesi Orthopaedic Surgery

Author Mark Erik Easley Orthopaedic Surgery

Author James Albert Nunley II Orthopaedic Surgery

Author Sean Ryan Orthopaedic Surgery

Published In

J Arthroplasty

DOI

10.1016/j.arth.2025.03.043

EISSN

1532-8406

Publication Date

July 2025

Volume

Issue

7S1

Start / End Page

S158 / S168

Location

United States

Related Subject Headings

Treatment Outcome
Retrospective Studies
Propensity Score
Patient Reported Outcome Measures
Orthopedics
Middle Aged
Male
Humans
Female
Arthroplasty, Replacement, Knee

Citation

APA

Chicago

ICMJE

MLA

NLM

Leal, J., Holland, C. T., Wu, C. J., Easley, M. E., Nunley, J. A., Ryan, S. P., … Jiranek, W. A. (2025). Are There Differences in Patient-Reported Outcomes Measurement Information System Scores After Total Knee and Total Ankle Arthroplasty in Matched Patients? J Arthroplasty, 40(7S1), S158–S168. https://doi.org/10.1016/j.arth.2025.03.043

Leal, Justin, Christopher T. Holland, Christine J. Wu, Mark E. Easley, James A. Nunley, Sean P. Ryan, Michael P. Bolognesi, Samuel S. Wellman, and William A. Jiranek. “Are There Differences in Patient-Reported Outcomes Measurement Information System Scores After Total Knee and Total Ankle Arthroplasty in Matched Patients?” J Arthroplasty 40, no. 7S1 (July 2025): S158–68. https://doi.org/10.1016/j.arth.2025.03.043.

Leal J, Holland CT, Wu CJ, Easley ME, Nunley JA, Ryan SP, et al. Are There Differences in Patient-Reported Outcomes Measurement Information System Scores After Total Knee and Total Ankle Arthroplasty in Matched Patients? J Arthroplasty. 2025 Jul;40(7S1):S158–68.

Leal, Justin, et al. “Are There Differences in Patient-Reported Outcomes Measurement Information System Scores After Total Knee and Total Ankle Arthroplasty in Matched Patients?” J Arthroplasty, vol. 40, no. 7S1, July 2025, pp. S158–68. Pubmed, doi:10.1016/j.arth.2025.03.043.

Leal J, Holland CT, Wu CJ, Easley ME, Nunley JA, Ryan SP, Bolognesi MP, Wellman SS, Jiranek WA. Are There Differences in Patient-Reported Outcomes Measurement Information System Scores After Total Knee and Total Ankle Arthroplasty in Matched Patients? J Arthroplasty. 2025 Jul;40(7S1):S158–S168.