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Impact of young adult life transitions on adult mental health problems: a propensity score analysis.

Publication ,  Journal Article
Copeland, WE; Prytherch, S; Rothenberg, W; Godwin, JW; Gaydosh, L; Gutin, I; Tong, G; Shanahan, L
Published in: Psychol Med
May 19, 2025

BACKGROUND: Mental health problems commonly persist from childhood to adulthood. This study tested whether young adult life transitions can improve adult mental health symptoms after adjusting for childhood mental health symptoms. METHODS: The analysis uses data from the prospective, representative Great Smoky Mountains Study. Life transitions (e.g., high school completion, partnering, parenthood, and living independently) were assessed up to three times in young adulthood (ages 18 to 26; 3,241 observations). A cumulative variable counted the number of young adult transitions. Emotional, substance use, and antisocial personality symptoms were assessed at age 30 (1,154 participants or 81.2% of the original sample). Propensity models adjusted for early life adversities and psychiatric symptoms. RESULTS: Multiple young adult transitions were common (m = 4.62; SD = 1.57). After adjusting for childhood mental health problems and adversities, each additional transition was significantly associated with a reduction in subsequent adult emotional symptoms (β = -0.34, 95% CI: -0.59, -0.08, p = 0.01) and adult antisocial personality disorder symptoms (β = -0.08, 95% CI: -0.14, -0.02, p < 0.001. These associations were stronger in males than in females. Young adult transitions were not associated with reductions in subsequent substance use symptoms (β = -0.04; 95% CI: -0.11, 0.03, p = 0.30). Young adult transitions related to educational milestones and consistent employment were associated with the largest reductions in symptoms. CONCLUSIONS: In this cohort study, life transitions during young adulthood were associated with reduced emotional and behavioral symptoms in adulthood. These transitions may constitute a potential mental health turning point and a specific, modifiable target for social policies.

Duke Scholars

Published In

Psychol Med

DOI

EISSN

1469-8978

Publication Date

May 19, 2025

Volume

55

Start / End Page

e152

Location

England

Related Subject Headings

  • Young Adult
  • Substance-Related Disorders
  • Psychiatry
  • Prospective Studies
  • Propensity Score
  • Mental Disorders
  • Male
  • Life Change Events
  • Humans
  • Female
 

Citation

APA
Chicago
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Copeland, W. E., Prytherch, S., Rothenberg, W., Godwin, J. W., Gaydosh, L., Gutin, I., … Shanahan, L. (2025). Impact of young adult life transitions on adult mental health problems: a propensity score analysis. Psychol Med, 55, e152. https://doi.org/10.1017/S0033291725001072
Copeland, William E., Shania Prytherch, W. Rothenberg, Jennifer W. Godwin, Lauren Gaydosh, Iliya Gutin, Guangyu Tong, and Lilly Shanahan. “Impact of young adult life transitions on adult mental health problems: a propensity score analysis.Psychol Med 55 (May 19, 2025): e152. https://doi.org/10.1017/S0033291725001072.
Copeland WE, Prytherch S, Rothenberg W, Godwin JW, Gaydosh L, Gutin I, et al. Impact of young adult life transitions on adult mental health problems: a propensity score analysis. Psychol Med. 2025 May 19;55:e152.
Copeland, William E., et al. “Impact of young adult life transitions on adult mental health problems: a propensity score analysis.Psychol Med, vol. 55, May 2025, p. e152. Pubmed, doi:10.1017/S0033291725001072.
Copeland WE, Prytherch S, Rothenberg W, Godwin JW, Gaydosh L, Gutin I, Tong G, Shanahan L. Impact of young adult life transitions on adult mental health problems: a propensity score analysis. Psychol Med. 2025 May 19;55:e152.
Journal cover image

Published In

Psychol Med

DOI

EISSN

1469-8978

Publication Date

May 19, 2025

Volume

55

Start / End Page

e152

Location

England

Related Subject Headings

  • Young Adult
  • Substance-Related Disorders
  • Psychiatry
  • Prospective Studies
  • Propensity Score
  • Mental Disorders
  • Male
  • Life Change Events
  • Humans
  • Female