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Ten years later: how is AI impacting retina care today?

Publication ,  Journal Article
Kuo, D; Pajic, M; Hadziahmetovic, M
Published in: Current opinion in ophthalmology
August 2025

Artificial intelligence (AI) is transforming retina care, with deep learning (DL) models shaping a new era of improved screening accessibility, diagnostic precision, and personalized disease monitoring. This review highlights recent AI-powered clinical applications in diabetic retinopathy (DR), and age-related macular degeneration (AMD) care.Since the FDA's authorization of the first autonomous AI system for DR screening in 2018, multiple platforms have emerged, expanding access to diabetic eye care. Real-world studies have confirmed a significant improvement in screening adherence and diagnostic accuracy, illustrating AI's tangible impact on public health. Meanwhile, newly certified AI technologies that meet European regulatory standards are increasingly guiding clinical decision-making in the management of AMD and diabetic macular edema through automated analysis of optical coherence tomography (OCT) images. Most recently, FDA-authorized home OCT platforms are transforming AMD monitoring, enabling proactive and remote management of retinal fluid.As AI increasingly empowers patients and providers, its widespread success still depends on ongoing work, including thorough validation, outcome-based metrics, and improved workflow integration. The next decade will reveal whether AI in retina care transitions from a promising innovation to an essential and indispensable tool in modern retina.

Duke Scholars

Published In

Current opinion in ophthalmology

DOI

EISSN

1531-7021

ISSN

1040-8738

Publication Date

August 2025

Related Subject Headings

  • Ophthalmology & Optometry
  • 3212 Ophthalmology and optometry
  • 1113 Opthalmology and Optometry
 

Citation

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Kuo, D., Pajic, M., & Hadziahmetovic, M. (2025). Ten years later: how is AI impacting retina care today? Current Opinion in Ophthalmology. https://doi.org/10.1097/icu.0000000000001167
Kuo, David, Miroslav Pajic, and Majda Hadziahmetovic. “Ten years later: how is AI impacting retina care today?Current Opinion in Ophthalmology, August 2025. https://doi.org/10.1097/icu.0000000000001167.
Kuo D, Pajic M, Hadziahmetovic M. Ten years later: how is AI impacting retina care today? Current opinion in ophthalmology. 2025 Aug;
Kuo, David, et al. “Ten years later: how is AI impacting retina care today?Current Opinion in Ophthalmology, Aug. 2025. Epmc, doi:10.1097/icu.0000000000001167.
Kuo D, Pajic M, Hadziahmetovic M. Ten years later: how is AI impacting retina care today? Current opinion in ophthalmology. 2025 Aug;

Published In

Current opinion in ophthalmology

DOI

EISSN

1531-7021

ISSN

1040-8738

Publication Date

August 2025

Related Subject Headings

  • Ophthalmology & Optometry
  • 3212 Ophthalmology and optometry
  • 1113 Opthalmology and Optometry