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Operating Room Black Box Technology to Mitigate Local Anesthetic Systemic Toxicity Risk Associated With Liposomal Bupivacaine Administration.

Publication ,  Journal Article
Lee, G; Turner, BS; Szydlowski, JD; Simmons, VC
Published in: Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses
December 2025

This quality improvement project used operating room black box (ORBB) technology to evaluate adherence to liposomal bupivacaine (LB) administration protocols, specifically to identify obstacles to compliance with these protocols to mitigate the risk of local anesthetic systemic toxicity (LAST).The team conducted a retrospective chart review of surgical cases using ORBB technology in two robotic operating rooms at a tertiary academic medical center.The project included 39 patients who received intraoperative LB between November 2022 and February 2024. Data were collected from the ORBB recordings and electronic medical records, focusing on provider adherence to LB administration protocols, such as conducting LB time-outs, applying LB alert wristbands, discontinuing lidocaine infusions, and following a 2:1 admixture ratio of LB with bupivacaine hydrochloride.Chart review indicated 25 (64%) cases completed the LB time-out, 24 (62%) applied the LB wristband intraoperatively, 23 (59%) included a wristband check, and 14 (36%) incorporated lidocaine infusion checks during the LB time-out. One case failed to stop the lidocaine infusion and 3 cases failed to follow the correct 2:1 admixture ratio; however, no LAST cases were reported.These findings underscore the potential of ORBB technology in improving adherence to LB administration protocols, reducing the incidence of LAST (10.2%), and enhancing patient safety. Challenges such as blind zones in ORBB coverage, the Hawthorne effect, and potential litigation risks are acknowledged. Information and training about ORBB technology, sharing ORBB reports with staff, and cross-referencing ORBB data with electronic medical records are recommended to optimize patient outcomes.

Duke Scholars

Published In

Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses

DOI

EISSN

1532-8473

ISSN

1089-9472

Publication Date

December 2025

Volume

40

Issue

6

Start / End Page

1431 / 1437

Related Subject Headings

  • Retrospective Studies
  • Quality Improvement
  • Operating Rooms
  • Nursing
  • Middle Aged
  • Male
  • Liposomes
  • Humans
  • Female
  • Bupivacaine
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Lee, G., Turner, B. S., Szydlowski, J. D., & Simmons, V. C. (2025). Operating Room Black Box Technology to Mitigate Local Anesthetic Systemic Toxicity Risk Associated With Liposomal Bupivacaine Administration. Journal of Perianesthesia Nursing : Official Journal of the American Society of PeriAnesthesia Nurses, 40(6), 1431–1437. https://doi.org/10.1016/j.jopan.2025.02.016
Lee, Gyuhyun, Barbara S. Turner, Jessica D. Szydlowski, and Virginia C. Simmons. “Operating Room Black Box Technology to Mitigate Local Anesthetic Systemic Toxicity Risk Associated With Liposomal Bupivacaine Administration.Journal of Perianesthesia Nursing : Official Journal of the American Society of PeriAnesthesia Nurses 40, no. 6 (December 2025): 1431–37. https://doi.org/10.1016/j.jopan.2025.02.016.
Lee G, Turner BS, Szydlowski JD, Simmons VC. Operating Room Black Box Technology to Mitigate Local Anesthetic Systemic Toxicity Risk Associated With Liposomal Bupivacaine Administration. Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses. 2025 Dec;40(6):1431–7.
Lee, Gyuhyun, et al. “Operating Room Black Box Technology to Mitigate Local Anesthetic Systemic Toxicity Risk Associated With Liposomal Bupivacaine Administration.Journal of Perianesthesia Nursing : Official Journal of the American Society of PeriAnesthesia Nurses, vol. 40, no. 6, Dec. 2025, pp. 1431–37. Epmc, doi:10.1016/j.jopan.2025.02.016.
Lee G, Turner BS, Szydlowski JD, Simmons VC. Operating Room Black Box Technology to Mitigate Local Anesthetic Systemic Toxicity Risk Associated With Liposomal Bupivacaine Administration. Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses. 2025 Dec;40(6):1431–1437.
Journal cover image

Published In

Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses

DOI

EISSN

1532-8473

ISSN

1089-9472

Publication Date

December 2025

Volume

40

Issue

6

Start / End Page

1431 / 1437

Related Subject Headings

  • Retrospective Studies
  • Quality Improvement
  • Operating Rooms
  • Nursing
  • Middle Aged
  • Male
  • Liposomes
  • Humans
  • Female
  • Bupivacaine