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Prevalence of Tobacco Use in Adults with Chronic Pain: Results from the National Health Interview Survey 2014-2023.

Publication ,  Journal Article
Lazzari, J; Rubenstein, D; Powers, JM; Keefe, FJ; McClernon, FJ; Pacek, LR; Sweitzer, MM
Published in: Am J Prev Med
December 26, 2025

INTRODUCTION: Chronic pain is linked to elevated tobacco use, but long-term trends in combustible smoking and e-cigarette use in this group remain unclear. Understanding these trajectories is vital for designing effective public health interventions. This study examined national trends in exclusive cigarette smoking (E-CS), exclusive e-cigarette use (E-EC), and dual use (2014-2023) among United States (U.S.) adults with and without chronic pain. METHODS: This was a serial cross-sectional analysis using 2014-2023 (excluding 2022) National Health Interview Survey data from 195,632 U.S. adults. Chronic pain (yes/no) was defined by self-reported pain frequency (past 3 months): "everyday" or "most days" versus "some days" or "never". Primary outcomes were E-CS, E-EC, and dual use prevalence by pain status and year, assessed via logistic regression. Secondary analyses examined pain frequency (continuous) and high-impact chronic pain (yes/no). Analyses were conducted in 2025. RESULTS: E-CS prevalence was significantly higher and declined more slowly among individuals with chronic pain (17.7%-2014, 13.1%-2023) versus without (12.5%-2014, 7.5%-2023; p<0.001). Adjusting for age, sex, and race/ethnicity, both E-EC and dual use prevalence were higher in the chronic pain group across all years. E-EC use increased at similar rates among individuals with (1.4%-2014, 5.6%-2023) and without (1.2%-2014, 4.5%-2023; p's<0.001) chronic pain; dual use prevalence declined at similar rates among individuals with (4.6%-2014, 2.7%-2023) and without (2.3%-2014, 1.5%-2023) chronic pain. CONCLUSIONS: While U.S. E-CS prevalence has decreased, individuals with chronic pain remain disproportionately impacted, emphasizing the need for targeted tobacco interventions.

Duke Scholars

Published In

Am J Prev Med

DOI

EISSN

1873-2607

Publication Date

December 26, 2025

Start / End Page

108251

Location

Netherlands

Related Subject Headings

  • Public Health
  • 42 Health sciences
  • 39 Education
  • 32 Biomedical and clinical sciences
  • 13 Education
  • 11 Medical and Health Sciences
 

Citation

APA
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Lazzari, J., Rubenstein, D., Powers, J. M., Keefe, F. J., McClernon, F. J., Pacek, L. R., & Sweitzer, M. M. (2025). Prevalence of Tobacco Use in Adults with Chronic Pain: Results from the National Health Interview Survey 2014-2023. Am J Prev Med, 108251. https://doi.org/10.1016/j.amepre.2025.108251
Lazzari, Julianna, Dana Rubenstein, Jessica M. Powers, Francis J. Keefe, F Joseph McClernon, Lauren R. Pacek, and Maggie M. Sweitzer. “Prevalence of Tobacco Use in Adults with Chronic Pain: Results from the National Health Interview Survey 2014-2023.Am J Prev Med, December 26, 2025, 108251. https://doi.org/10.1016/j.amepre.2025.108251.
Lazzari J, Rubenstein D, Powers JM, Keefe FJ, McClernon FJ, Pacek LR, et al. Prevalence of Tobacco Use in Adults with Chronic Pain: Results from the National Health Interview Survey 2014-2023. Am J Prev Med. 2025 Dec 26;108251.
Lazzari, Julianna, et al. “Prevalence of Tobacco Use in Adults with Chronic Pain: Results from the National Health Interview Survey 2014-2023.Am J Prev Med, Dec. 2025, p. 108251. Pubmed, doi:10.1016/j.amepre.2025.108251.
Lazzari J, Rubenstein D, Powers JM, Keefe FJ, McClernon FJ, Pacek LR, Sweitzer MM. Prevalence of Tobacco Use in Adults with Chronic Pain: Results from the National Health Interview Survey 2014-2023. Am J Prev Med. 2025 Dec 26;108251.
Journal cover image

Published In

Am J Prev Med

DOI

EISSN

1873-2607

Publication Date

December 26, 2025

Start / End Page

108251

Location

Netherlands

Related Subject Headings

  • Public Health
  • 42 Health sciences
  • 39 Education
  • 32 Biomedical and clinical sciences
  • 13 Education
  • 11 Medical and Health Sciences