Overview
The primary focus of my research program involves elucidating neurobehavioral mechanisms underlying addictive disorders, and translating this knowledge to develop more efficacious interventions. Much of my work has emphasized dysregulated reward processing and cognitive control as key trans-diagnostic mechanisms contributing to high rates of comorbidity between cigarette smoking and psychiatric disorders, and ultimately increasing vulnerability to relapse. In addressing these topics, I combine methods including functional neuroimaging, laboratory behavioral pharmacology, and ecological momentary assessment. My ongoing projects focus on two primary areas: 1) neurobehavioral mechanisms contributing to risk for substance use among young adults with a history childhood adversity; and 2) identifying mechanisms and intervention targets in comorbidity between tobacco use and chronic pain.
Current Appointments & Affiliations
Associate Professor in Psychiatry and Behavioral Sciences
·
2024 - Present
Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences,
Psychiatry & Behavioral Sciences
Member of the Center for Brain Imaging and Analysis
·
2016 - Present
Duke-UNC Brain Imaging and Analysis Center,
Institutes and Centers
Member of the Duke Cancer Institute
·
2022 - Present
Duke Cancer Institute,
Institutes and Centers
Recent Publications
Ecological momentary assessment of cigarette smoking behavior and pain intensity among individuals with chronic back pain who smoke.
Journal Article J Pain · March 2025 Chronic pain affects ∼20% of the adult population and is associated with smoking. Smoking and pain worsen each other in the long term, but short-term temporal associations between smoking and pain throughout the day are unclear. Understanding these relatio ... Full text Link to item CiteAssociations between compliance with very low nicotine content (VLNC) cigarettes, abstinence self-efficacy, and quit outcomes in a pilot smoking cessation trial.
Journal Article Drug Alcohol Depend · September 1, 2024 BACKGROUND: Switching to Very Low Nicotine Content (VLNC) cigarettes reduces toxicant exposure and nicotine dependence, and may improve smoking cessation. However, non-compliance with VLNCs is often high, which may reduce their effectiveness. Here, we cond ... Full text Link to item CiteReactions to reduced nicotine content cigarettes in a sample of young adult, low-frequency smokers.
Journal Article Psychopharmacology (Berl) · September 2021 RATIONALE: Reducing nicotine content in cigarettes to ≤ 2.4 mg per g of tobacco [mg/g] reduces smoking behavior and toxicant exposure among adult daily smokers. However, cigarettes with similar nicotine content could support continued experimentation and s ... Full text Link to item CiteRecent Grants
Targeting Reinforcement Mechanisms for Smoking Cessation Using Very Low Nicotine Content Cigarettes in Individuals with Opioid Use Disorder and Chronic Pain
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2024 - 2027Neurobehavioral mechanisms linking childhood adversity to increased risk for smoking
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2022 - 2027Mental health and Bolsa Familia: A mechanistically focused clinical trial of a cash transfer intervention on child brain, behavior, and mental health
ResearchCo Investigator · Awarded by Research Foundation for Mental Hygiene, Inc. · 2022 - 2027View All Grants
Education, Training & Certifications
University of Pittsburgh ·
2013
Ph.D.