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Fungal phospholipase activity and susceptibility to lipid preparations of amphotericin B.

Publication ,  Journal Article
Gottfredsson, M; Jessup, CJ; Cox, GM; Perfect, JR; Ghannoum, MA
Published in: Antimicrob Agents Chemother
November 2001

It has been postulated that phospholipases of fungal origin can affect in vitro susceptibility testing of amphotericin B lipid complex (ABLC). We used specific phospholipase-deficient mutants of Candida albicans and Cryptococcus neoformans in susceptibility testing and demonstrated that extracellular fungal phospholipase activity does not influence the in vitro susceptibilities of these two fungi to ABLC.

Duke Scholars

Published In

Antimicrob Agents Chemother

DOI

ISSN

0066-4804

Publication Date

November 2001

Volume

45

Issue

11

Start / End Page

3231 / 3233

Location

United States

Related Subject Headings

  • Microbiology
  • Microbial Sensitivity Tests
  • Lysophospholipase
  • Liposomes
  • Fungi
  • Drug Carriers
  • Antifungal Agents
  • Amphotericin B
  • 3214 Pharmacology and pharmaceutical sciences
  • 3207 Medical microbiology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Gottfredsson, M., Jessup, C. J., Cox, G. M., Perfect, J. R., & Ghannoum, M. A. (2001). Fungal phospholipase activity and susceptibility to lipid preparations of amphotericin B. Antimicrob Agents Chemother, 45(11), 3231–3233. https://doi.org/10.1128/AAC.45.11.3231-3233.2001
Gottfredsson, M., C. J. Jessup, G. M. Cox, J. R. Perfect, and M. A. Ghannoum. “Fungal phospholipase activity and susceptibility to lipid preparations of amphotericin B.Antimicrob Agents Chemother 45, no. 11 (November 2001): 3231–33. https://doi.org/10.1128/AAC.45.11.3231-3233.2001.
Gottfredsson M, Jessup CJ, Cox GM, Perfect JR, Ghannoum MA. Fungal phospholipase activity and susceptibility to lipid preparations of amphotericin B. Antimicrob Agents Chemother. 2001 Nov;45(11):3231–3.
Gottfredsson, M., et al. “Fungal phospholipase activity and susceptibility to lipid preparations of amphotericin B.Antimicrob Agents Chemother, vol. 45, no. 11, Nov. 2001, pp. 3231–33. Pubmed, doi:10.1128/AAC.45.11.3231-3233.2001.
Gottfredsson M, Jessup CJ, Cox GM, Perfect JR, Ghannoum MA. Fungal phospholipase activity and susceptibility to lipid preparations of amphotericin B. Antimicrob Agents Chemother. 2001 Nov;45(11):3231–3233.

Published In

Antimicrob Agents Chemother

DOI

ISSN

0066-4804

Publication Date

November 2001

Volume

45

Issue

11

Start / End Page

3231 / 3233

Location

United States

Related Subject Headings

  • Microbiology
  • Microbial Sensitivity Tests
  • Lysophospholipase
  • Liposomes
  • Fungi
  • Drug Carriers
  • Antifungal Agents
  • Amphotericin B
  • 3214 Pharmacology and pharmaceutical sciences
  • 3207 Medical microbiology