EEG correlates of the response to ECT: a possible antidepressant role of brain-derived neurotrophic factor.
Studies on the relationship of electroencephalographic (EEG) data to the therapeutic response to electroconvulsive therapy (ECT) have been carried out since the 1940s, but for many years they did not yield any consistent correlates. Recent studies, however, are providing a growing body of evidence of relationships between the antidepressant response to ECT and both the ictal (recorded during ECT seizures) and interictal (recorded during waking) EEG. These studies appear to be consistent in pointing to the importance of electrophysiologic changes in the prefrontal cortex as a potential mediator of the antidepressant response to ECT. The available findings are reviewed and discussed in light of recent neurophysiologic and neuropsychiatric research, including that related to neurotrophic factors.
Duke Scholars
Published In
ISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- Psychiatry
- Prefrontal Cortex
- Nerve Tissue Proteins
- Nerve Growth Factors
- Humans
- Electroencephalography
- Electroconvulsive Therapy
- Depressive Disorder
- 5203 Clinical and health psychology
- 3209 Neurosciences
Citation
Published In
ISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- Psychiatry
- Prefrontal Cortex
- Nerve Tissue Proteins
- Nerve Growth Factors
- Humans
- Electroencephalography
- Electroconvulsive Therapy
- Depressive Disorder
- 5203 Clinical and health psychology
- 3209 Neurosciences