Preparation and evaluation of a cyclic acyl nitrone as a synthon for stereospecific α-amino acid synthesis
Publication
, Journal Article
Baldwin, SW; Young, BG; McPhail, AT
Published in: Tetrahedron Letters
September 17, 1998
The preparation and characterization of cyclic optically active (5R)- 3,4,5,6-tetrahydro-5-phenyl-2H-1,4-oxazin-2-one-N-oxide (2) is described. This nitrone, which is viewed as a template for the synthesis of γ- oxygenated α-amino acids, reacts with alkenes efficiently and with high stereospecificity.
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Published In
Tetrahedron Letters
DOI
ISSN
0040-4039
Publication Date
September 17, 1998
Volume
39
Issue
38
Start / End Page
6819 / 6822
Related Subject Headings
- Organic Chemistry
- 3405 Organic chemistry
- 3404 Medicinal and biomolecular chemistry
- 3101 Biochemistry and cell biology
- 0305 Organic Chemistry
- 0304 Medicinal and Biomolecular Chemistry
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Baldwin, S. W., Young, B. G., & McPhail, A. T. (1998). Preparation and evaluation of a cyclic acyl nitrone as a synthon for stereospecific α-amino acid synthesis. Tetrahedron Letters, 39(38), 6819–6822. https://doi.org/10.1016/S0040-4039(98)01474-9
Baldwin, S. W., B. G. Young, and A. T. McPhail. “Preparation and evaluation of a cyclic acyl nitrone as a synthon for stereospecific α-amino acid synthesis.” Tetrahedron Letters 39, no. 38 (September 17, 1998): 6819–22. https://doi.org/10.1016/S0040-4039(98)01474-9.
Baldwin SW, Young BG, McPhail AT. Preparation and evaluation of a cyclic acyl nitrone as a synthon for stereospecific α-amino acid synthesis. Tetrahedron Letters. 1998 Sep 17;39(38):6819–22.
Baldwin, S. W., et al. “Preparation and evaluation of a cyclic acyl nitrone as a synthon for stereospecific α-amino acid synthesis.” Tetrahedron Letters, vol. 39, no. 38, Sept. 1998, pp. 6819–22. Scopus, doi:10.1016/S0040-4039(98)01474-9.
Baldwin SW, Young BG, McPhail AT. Preparation and evaluation of a cyclic acyl nitrone as a synthon for stereospecific α-amino acid synthesis. Tetrahedron Letters. 1998 Sep 17;39(38):6819–6822.
Published In
Tetrahedron Letters
DOI
ISSN
0040-4039
Publication Date
September 17, 1998
Volume
39
Issue
38
Start / End Page
6819 / 6822
Related Subject Headings
- Organic Chemistry
- 3405 Organic chemistry
- 3404 Medicinal and biomolecular chemistry
- 3101 Biochemistry and cell biology
- 0305 Organic Chemistry
- 0304 Medicinal and Biomolecular Chemistry