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Hippocampal sulcal cavities on MRI: relationship to age and apolipoprotein E genotype.

Publication ,  Journal Article
Barboriak, DP; Doraiswamy, PM; Krishnan, KR; Vidyarthi, S; Sylvester, J; Charles, HC
Published in: Neurology
June 13, 2000

Hippocampal sulcal cavities are usually considered incidental findings on brain MRI. In a group of 92 elderly volunteers, the authors graded the number and size of hippocampal sulcal cavities with brain MRI to obtain a cavity score. Cavity scores increased with age, and were higher in subjects carrying the APOE epsilon4 or epsilon2 alleles than in subjects with the epsilon3/3 genotype. Age-related morphologic changes in the hippocampus may be mediated by the APOE genotype.

Duke Scholars

Published In

Neurology

DOI

ISSN

0028-3878

Publication Date

June 13, 2000

Volume

54

Issue

11

Start / End Page

2150 / 2153

Location

United States

Related Subject Headings

  • Neurology & Neurosurgery
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging
  • Linear Models
  • Humans
  • Hippocampus
  • Genotype
  • Female
  • Apolipoproteins E
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Barboriak, D. P., Doraiswamy, P. M., Krishnan, K. R., Vidyarthi, S., Sylvester, J., & Charles, H. C. (2000). Hippocampal sulcal cavities on MRI: relationship to age and apolipoprotein E genotype. Neurology, 54(11), 2150–2153. https://doi.org/10.1212/wnl.54.11.2150
Barboriak, D. P., P. M. Doraiswamy, K. R. Krishnan, S. Vidyarthi, J. Sylvester, and H. C. Charles. “Hippocampal sulcal cavities on MRI: relationship to age and apolipoprotein E genotype.Neurology 54, no. 11 (June 13, 2000): 2150–53. https://doi.org/10.1212/wnl.54.11.2150.
Barboriak DP, Doraiswamy PM, Krishnan KR, Vidyarthi S, Sylvester J, Charles HC. Hippocampal sulcal cavities on MRI: relationship to age and apolipoprotein E genotype. Neurology. 2000 Jun 13;54(11):2150–3.
Barboriak, D. P., et al. “Hippocampal sulcal cavities on MRI: relationship to age and apolipoprotein E genotype.Neurology, vol. 54, no. 11, June 2000, pp. 2150–53. Pubmed, doi:10.1212/wnl.54.11.2150.
Barboriak DP, Doraiswamy PM, Krishnan KR, Vidyarthi S, Sylvester J, Charles HC. Hippocampal sulcal cavities on MRI: relationship to age and apolipoprotein E genotype. Neurology. 2000 Jun 13;54(11):2150–2153.

Published In

Neurology

DOI

ISSN

0028-3878

Publication Date

June 13, 2000

Volume

54

Issue

11

Start / End Page

2150 / 2153

Location

United States

Related Subject Headings

  • Neurology & Neurosurgery
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging
  • Linear Models
  • Humans
  • Hippocampus
  • Genotype
  • Female
  • Apolipoproteins E