Scholars@Duke publication: Biodemographic trajectories of longevity.

Biodemographic trajectories of longevity.

Publication , Journal Article

Vaupel, JW; Carey, JR; Christensen, K; Johnson, TE; Yashin, AI; Holm, NV; Iachine, IA; Kannisto, V; Khazaeli, AA; Liedo, P; Longo, VD; Zeng, Y ...

Published in: Science

May 8, 1998

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Old-age survival has increased substantially since 1950. Death rates decelerate with age for insects, worms, and yeast, as well as humans. This evidence of extended postreproductive survival is puzzling. Three biodemographic insights--concerning the correlation of death rates across age, individual differences in survival chances, and induced alterations in age patterns of fertility and mortality--offer clues and suggest research on the failure of complicated systems, on new demographic equations for evolutionary theory, and on fertility-longevity interactions. Nongenetic changes account for increases in human life-spans to date. Explication of these causes and the genetic license for extended survival, as well as discovery of genes and other survival attributes affecting longevity, will lead to even longer lives.

Duke Scholars

Author Anatoli I. Yashin Social Science Research Institute

Author Yi Zeng Medicine, Geriatrics and Palliative Care

Author Kenneth G. Manton Trinity College of Arts & Sciences

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Published In

Science

DOI

10.1126/science.280.5365.855

ISSN

0036-8075

Publication Date

May 8, 1998

Volume

280

Issue

5365

Start / End Page

855 / 860

Location

United States

Related Subject Headings

Mortality
Models, Statistical
Male
Longevity
Humans
Genetic Variation
Genes
General Science & Technology
Fertility
Female

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Vaupel, J. W., Carey, J. R., Christensen, K., Johnson, T. E., Yashin, A. I., Holm, N. V., … Curtsinger, J. W. (1998). Biodemographic trajectories of longevity. Science, 280(5365), 855–860. https://doi.org/10.1126/science.280.5365.855

Vaupel, J. W., J. R. Carey, K. Christensen, T. E. Johnson, A. I. Yashin, N. V. Holm, I. A. Iachine, et al. “Biodemographic trajectories of longevity.” Science 280, no. 5365 (May 8, 1998): 855–60. https://doi.org/10.1126/science.280.5365.855.

Vaupel JW, Carey JR, Christensen K, Johnson TE, Yashin AI, Holm NV, et al. Biodemographic trajectories of longevity. Science. 1998 May 8;280(5365):855–60.

Vaupel, J. W., et al. “Biodemographic trajectories of longevity.” Science, vol. 280, no. 5365, May 1998, pp. 855–60. Pubmed, doi:10.1126/science.280.5365.855.

Vaupel JW, Carey JR, Christensen K, Johnson TE, Yashin AI, Holm NV, Iachine IA, Kannisto V, Khazaeli AA, Liedo P, Longo VD, Zeng Y, Manton KG, Curtsinger JW. Biodemographic trajectories of longevity. Science. 1998 May 8;280(5365):855–860.

Published In

Science

DOI

10.1126/science.280.5365.855

ISSN

0036-8075

Publication Date

May 8, 1998

Volume

280

Issue

5365

Start / End Page

855 / 860

Location

United States

Related Subject Headings

Mortality
Models, Statistical
Male
Longevity
Humans
Genetic Variation
Genes
General Science & Technology
Fertility
Female