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Incidence and impact on outcome of streptokinase allergy in the GUSTO-I trial. Global Utilization of Streptokinase and t-PA in Occluded Coronary Arteries.

Publication ,  Journal Article
Tsang, TS; Califf, RM; Stebbins, AL; Lee, KL; Cho, S; Ross, AM; Armstrong, PW
Published in: Am J Cardiol
May 1, 1997

We evaluated allergic reactions in 20,201 patients randomized to the streptokinase arms of The Global Utilization of Streptokinase and t-PA (Tissue Plasminogen Activator) in Occluded Coronary Arteries (GUSTO-I) trial, and tested the hypothesis that patients with streptokinase allergy would exhibit higher mortality. After adjusting for baseline variables and time of death, we found comparable coronary patency, left ventricular function, mortality, and bleeding complications between patients with versus those without streptokinase allergy.

Duke Scholars

Published In

Am J Cardiol

DOI

ISSN

0002-9149

Publication Date

May 1, 1997

Volume

79

Issue

9

Start / End Page

1232 / 1235

Location

United States

Related Subject Headings

  • Tissue Plasminogen Activator
  • Survival Rate
  • Streptokinase
  • Regression Analysis
  • Myocardial Infarction
  • Middle Aged
  • Male
  • Incidence
  • Humans
  • Female
 

Citation

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Tsang, T. S., Califf, R. M., Stebbins, A. L., Lee, K. L., Cho, S., Ross, A. M., & Armstrong, P. W. (1997). Incidence and impact on outcome of streptokinase allergy in the GUSTO-I trial. Global Utilization of Streptokinase and t-PA in Occluded Coronary Arteries. Am J Cardiol, 79(9), 1232–1235. https://doi.org/10.1016/s0002-9149(97)00087-8
Tsang, T. S., R. M. Califf, A. L. Stebbins, K. L. Lee, S. Cho, A. M. Ross, and P. W. Armstrong. “Incidence and impact on outcome of streptokinase allergy in the GUSTO-I trial. Global Utilization of Streptokinase and t-PA in Occluded Coronary Arteries.Am J Cardiol 79, no. 9 (May 1, 1997): 1232–35. https://doi.org/10.1016/s0002-9149(97)00087-8.
Tsang TS, Califf RM, Stebbins AL, Lee KL, Cho S, Ross AM, et al. Incidence and impact on outcome of streptokinase allergy in the GUSTO-I trial. Global Utilization of Streptokinase and t-PA in Occluded Coronary Arteries. Am J Cardiol. 1997 May 1;79(9):1232–5.
Tsang, T. S., et al. “Incidence and impact on outcome of streptokinase allergy in the GUSTO-I trial. Global Utilization of Streptokinase and t-PA in Occluded Coronary Arteries.Am J Cardiol, vol. 79, no. 9, May 1997, pp. 1232–35. Pubmed, doi:10.1016/s0002-9149(97)00087-8.
Tsang TS, Califf RM, Stebbins AL, Lee KL, Cho S, Ross AM, Armstrong PW. Incidence and impact on outcome of streptokinase allergy in the GUSTO-I trial. Global Utilization of Streptokinase and t-PA in Occluded Coronary Arteries. Am J Cardiol. 1997 May 1;79(9):1232–1235.
Journal cover image

Published In

Am J Cardiol

DOI

ISSN

0002-9149

Publication Date

May 1, 1997

Volume

79

Issue

9

Start / End Page

1232 / 1235

Location

United States

Related Subject Headings

  • Tissue Plasminogen Activator
  • Survival Rate
  • Streptokinase
  • Regression Analysis
  • Myocardial Infarction
  • Middle Aged
  • Male
  • Incidence
  • Humans
  • Female