
Malignant melanoma presenting as a mediastinal mass.
Publication
, Journal Article
Lau, CL; Bentley, RC; Gockerman, JP; Que, LG; D'Amico, TA
Published in: Ann Thorac Surg
March 1999
A case of malignant melanoma presenting as a mediastinal mass without an extrathoracic primary is reported. Microscopically the tumor appeared consistent with malignant melanoma, with the presence of focal melanin pigment in large epithelioid cells. Fontana stain confirmed the presence of melanin pigment. Immunohistochemical staining further suggested melanoma, with the tumor cells expressing a HMB45+, S100+ and cytokeratin-phenotype. Electron microscopy showed an abundance of melanosomes confirming the diagnosis of malignant melanoma.
Duke Scholars
Published In
Ann Thorac Surg
DOI
ISSN
0003-4975
Publication Date
March 1999
Volume
67
Issue
3
Start / End Page
851 / 852
Location
Netherlands
Related Subject Headings
- Respiratory System
- Radiography
- Melanoma
- Mediastinal Neoplasms
- Immunohistochemistry
- Humans
- Female
- Aged
- 3202 Clinical sciences
- 3201 Cardiovascular medicine and haematology
Citation
APA
Chicago
ICMJE
MLA
NLM
Lau, C. L., Bentley, R. C., Gockerman, J. P., Que, L. G., & D’Amico, T. A. (1999). Malignant melanoma presenting as a mediastinal mass. Ann Thorac Surg, 67(3), 851–852. https://doi.org/10.1016/s0003-4975(99)00075-2
Lau, C. L., R. C. Bentley, J. P. Gockerman, L. G. Que, and T. A. D’Amico. “Malignant melanoma presenting as a mediastinal mass.” Ann Thorac Surg 67, no. 3 (March 1999): 851–52. https://doi.org/10.1016/s0003-4975(99)00075-2.
Lau CL, Bentley RC, Gockerman JP, Que LG, D’Amico TA. Malignant melanoma presenting as a mediastinal mass. Ann Thorac Surg. 1999 Mar;67(3):851–2.
Lau, C. L., et al. “Malignant melanoma presenting as a mediastinal mass.” Ann Thorac Surg, vol. 67, no. 3, Mar. 1999, pp. 851–52. Pubmed, doi:10.1016/s0003-4975(99)00075-2.
Lau CL, Bentley RC, Gockerman JP, Que LG, D’Amico TA. Malignant melanoma presenting as a mediastinal mass. Ann Thorac Surg. 1999 Mar;67(3):851–852.

Published In
Ann Thorac Surg
DOI
ISSN
0003-4975
Publication Date
March 1999
Volume
67
Issue
3
Start / End Page
851 / 852
Location
Netherlands
Related Subject Headings
- Respiratory System
- Radiography
- Melanoma
- Mediastinal Neoplasms
- Immunohistochemistry
- Humans
- Female
- Aged
- 3202 Clinical sciences
- 3201 Cardiovascular medicine and haematology