Skip to main content

Using capsule endoscopy to identify GI tract lesions in cirrhotic patients with portal hypertension and chronic anemia.

Publication ,  Journal Article
Canlas, KR; Dobozi, BM; Lin, S; Smith, AD; Rockey, DC; Muir, AJ; Agrawal, NM; Poleski, MH; Patel, K; McHutchison, JG
Published in: J Clin Gastroenterol
August 2008

GOALS: We aimed to evaluate the ability of capsule endoscopy (CE) to detect small intestine (SI) lesions, especially SI varices, in patients with intrahepatic cirrhosis, portal hypertension (PHTN), and chronic anemia. BACKGROUND: Gastroesophageal variceal bleeding is a well-recognized complication of cirrhosis and PHTN, yet methods of identifying lesions in the SI that may contribute to covert bleeding and anemia, such as small bowel enteroscopy and angiography, are invasive and may be inadequate. STUDY: In this observational pilot study, 19 consecutive patients presenting to a tertiary care, liver transplantation referral center with cirrhosis, PHTN, and chronic anemia after obliterative esophageal variceal therapy were evaluated with wireless CE using the GIVEN Pillcam SB M2A capsule. Two independent and blinded examiners reviewed the CE examinations. RESULTS: SI varices were identified in 15.8% (3/19) of patients. Other PHTN-related findings included portal hypertensive gastropathy (13/19, 68.4%), portal hypertensive enteropathy (12/19, 63.1%), and portal hypertensive colopathy (3/19, 15.8%). Two patients had nonbleeding esophageal varices (2/19, 10.5%). A potential source of gastrointestinal blood loss was identified in 89.5% (17/19) of patients. Active bleeding sites were identified in 15.8% (3/19). CONCLUSIONS: CE can identify potential bleeding sources and could have diagnostic utility in patients with end-stage liver disease and chronic anemia after obliterative esophageal variceal therapy.

Duke Scholars

Published In

J Clin Gastroenterol

DOI

EISSN

1539-2031

Publication Date

August 2008

Volume

42

Issue

7

Start / End Page

844 / 848

Location

United States

Related Subject Headings

  • Middle Aged
  • Male
  • Liver Cirrhosis
  • Intestine, Small
  • Hypertension, Portal
  • Humans
  • Gastrointestinal Hemorrhage
  • Gastroenterology & Hepatology
  • Female
  • Esophageal and Gastric Varices
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Canlas, K. R., Dobozi, B. M., Lin, S., Smith, A. D., Rockey, D. C., Muir, A. J., … McHutchison, J. G. (2008). Using capsule endoscopy to identify GI tract lesions in cirrhotic patients with portal hypertension and chronic anemia. J Clin Gastroenterol, 42(7), 844–848. https://doi.org/10.1097/MCG.0b013e318038d312
Canlas, Karen R., Brian M. Dobozi, Sauyu Lin, Alastair D. Smith, Don C. Rockey, Andrew J. Muir, Naurang M. Agrawal, Martin H. Poleski, Keyur Patel, and John G. McHutchison. “Using capsule endoscopy to identify GI tract lesions in cirrhotic patients with portal hypertension and chronic anemia.J Clin Gastroenterol 42, no. 7 (August 2008): 844–48. https://doi.org/10.1097/MCG.0b013e318038d312.
Canlas KR, Dobozi BM, Lin S, Smith AD, Rockey DC, Muir AJ, et al. Using capsule endoscopy to identify GI tract lesions in cirrhotic patients with portal hypertension and chronic anemia. J Clin Gastroenterol. 2008 Aug;42(7):844–8.
Canlas, Karen R., et al. “Using capsule endoscopy to identify GI tract lesions in cirrhotic patients with portal hypertension and chronic anemia.J Clin Gastroenterol, vol. 42, no. 7, Aug. 2008, pp. 844–48. Pubmed, doi:10.1097/MCG.0b013e318038d312.
Canlas KR, Dobozi BM, Lin S, Smith AD, Rockey DC, Muir AJ, Agrawal NM, Poleski MH, Patel K, McHutchison JG. Using capsule endoscopy to identify GI tract lesions in cirrhotic patients with portal hypertension and chronic anemia. J Clin Gastroenterol. 2008 Aug;42(7):844–848.

Published In

J Clin Gastroenterol

DOI

EISSN

1539-2031

Publication Date

August 2008

Volume

42

Issue

7

Start / End Page

844 / 848

Location

United States

Related Subject Headings

  • Middle Aged
  • Male
  • Liver Cirrhosis
  • Intestine, Small
  • Hypertension, Portal
  • Humans
  • Gastrointestinal Hemorrhage
  • Gastroenterology & Hepatology
  • Female
  • Esophageal and Gastric Varices