Independent prognostic relevance of microvessel density in advanced epithelial ovarian cancer and associations between CD31, CD105, p53 status, and angiogenic marker expression: A Gynecologic Oncology Group study.
Publication
, Journal Article
Rubatt, JM; Darcy, KM; Hutson, A; Bean, SM; Havrilesky, LJ; Grace, LA; Berchuck, A; Secord, AA
Published in: Gynecol Oncol
March 2009
OBJECTIVES: The aims of this study were to examine prognostic significance of microvessel density (MVD) in previously-untreated, advanced epithelial ovarian cancer (EOC) and explore associations between MVD and factors that affect angiogenesis. METHODS: MVD was determined by immunohistochemical expression of CD31 or CD105 in tumor sections from 106 women treated on GOG randomized phase III trials. Average MVD hotspots were quantified by light microscopy at high power (x400) and categorized as low (
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Published In
Gynecol Oncol
DOI
EISSN
1095-6859
Publication Date
March 2009
Volume
112
Issue
3
Start / End Page
469 / 474
Location
United States
Related Subject Headings
- Vascular Endothelial Growth Factor Receptor-1
- Vascular Endothelial Growth Factor A
- Thrombospondin 1
- Serpins
- Receptors, Cell Surface
- Platelet Endothelial Cell Adhesion Molecule-1
- Ovarian Neoplasms
- Oncology & Carcinogenesis
- Neovascularization, Pathologic
- Middle Aged
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APA
Chicago
ICMJE
MLA
NLM
Rubatt, J. M., Darcy, K. M., Hutson, A., Bean, S. M., Havrilesky, L. J., Grace, L. A., … Secord, A. A. (2009). Independent prognostic relevance of microvessel density in advanced epithelial ovarian cancer and associations between CD31, CD105, p53 status, and angiogenic marker expression: A Gynecologic Oncology Group study. Gynecol Oncol, 112(3), 469–474. https://doi.org/10.1016/j.ygyno.2008.11.030
Rubatt, Jennifer M., Kathleen M. Darcy, Alan Hutson, Sarah M. Bean, Laura J. Havrilesky, Lisa A. Grace, Andrew Berchuck, and Angeles Alvarez Secord. “Independent prognostic relevance of microvessel density in advanced epithelial ovarian cancer and associations between CD31, CD105, p53 status, and angiogenic marker expression: A Gynecologic Oncology Group study.” Gynecol Oncol 112, no. 3 (March 2009): 469–74. https://doi.org/10.1016/j.ygyno.2008.11.030.
Rubatt JM, Darcy KM, Hutson A, Bean SM, Havrilesky LJ, Grace LA, et al. Independent prognostic relevance of microvessel density in advanced epithelial ovarian cancer and associations between CD31, CD105, p53 status, and angiogenic marker expression: A Gynecologic Oncology Group study. Gynecol Oncol. 2009 Mar;112(3):469–74.
Rubatt, Jennifer M., et al. “Independent prognostic relevance of microvessel density in advanced epithelial ovarian cancer and associations between CD31, CD105, p53 status, and angiogenic marker expression: A Gynecologic Oncology Group study.” Gynecol Oncol, vol. 112, no. 3, Mar. 2009, pp. 469–74. Pubmed, doi:10.1016/j.ygyno.2008.11.030.
Rubatt JM, Darcy KM, Hutson A, Bean SM, Havrilesky LJ, Grace LA, Berchuck A, Secord AA. Independent prognostic relevance of microvessel density in advanced epithelial ovarian cancer and associations between CD31, CD105, p53 status, and angiogenic marker expression: A Gynecologic Oncology Group study. Gynecol Oncol. 2009 Mar;112(3):469–474.
Published In
Gynecol Oncol
DOI
EISSN
1095-6859
Publication Date
March 2009
Volume
112
Issue
3
Start / End Page
469 / 474
Location
United States
Related Subject Headings
- Vascular Endothelial Growth Factor Receptor-1
- Vascular Endothelial Growth Factor A
- Thrombospondin 1
- Serpins
- Receptors, Cell Surface
- Platelet Endothelial Cell Adhesion Molecule-1
- Ovarian Neoplasms
- Oncology & Carcinogenesis
- Neovascularization, Pathologic
- Middle Aged