Giant cell interstitial pneumonia associated with nitrofurantoin.
Publication
, Journal Article
Hargett, CW; Sporn, TA; Roggli, VL; Hollingsworth, JW
Published in: Lung
2006
A case of giant cell interstitial pneumonia (GIF) that occurred in association with exposure to nitrofurantoin is presented. While the diagnosis of GIP is confirmed by histopathology, this diagnosis can be supported by the findings of bizarre multinucleated giant cells (MGC), elevated T lymphocytes, and a low T lymphocyte helper/suppressor ratio in the bronchoalveolar lavage fluid (BALF). Recognition of GIP as a rare manifestation of nitrofurantoin toxicity is important because prompt therapy may be associated with a favorable outcome.
Duke Scholars
Published In
Lung
DOI
ISSN
0341-2040
Publication Date
2006
Volume
184
Issue
3
Start / End Page
147 / 149
Location
United States
Related Subject Headings
- Urinary Tract Infections
- Respiratory System
- Nitrofurantoin
- Lung Diseases, Interstitial
- Humans
- Giant Cells
- Female
- Anti-Infective Agents, Urinary
- Aged
- 3201 Cardiovascular medicine and haematology
Citation
APA
Chicago
ICMJE
MLA
NLM
Hargett, C. W., Sporn, T. A., Roggli, V. L., & Hollingsworth, J. W. (2006). Giant cell interstitial pneumonia associated with nitrofurantoin. Lung, 184(3), 147–149. https://doi.org/10.1007/s00408-005-2574-z
Hargett, Charles William, Thomas A. Sporn, Victor L. Roggli, and John W. Hollingsworth. “Giant cell interstitial pneumonia associated with nitrofurantoin.” Lung 184, no. 3 (2006): 147–49. https://doi.org/10.1007/s00408-005-2574-z.
Hargett CW, Sporn TA, Roggli VL, Hollingsworth JW. Giant cell interstitial pneumonia associated with nitrofurantoin. Lung. 2006;184(3):147–9.
Hargett, Charles William, et al. “Giant cell interstitial pneumonia associated with nitrofurantoin.” Lung, vol. 184, no. 3, 2006, pp. 147–49. Pubmed, doi:10.1007/s00408-005-2574-z.
Hargett CW, Sporn TA, Roggli VL, Hollingsworth JW. Giant cell interstitial pneumonia associated with nitrofurantoin. Lung. 2006;184(3):147–149.
Published In
Lung
DOI
ISSN
0341-2040
Publication Date
2006
Volume
184
Issue
3
Start / End Page
147 / 149
Location
United States
Related Subject Headings
- Urinary Tract Infections
- Respiratory System
- Nitrofurantoin
- Lung Diseases, Interstitial
- Humans
- Giant Cells
- Female
- Anti-Infective Agents, Urinary
- Aged
- 3201 Cardiovascular medicine and haematology