Micro-CT imaging of breast tumors in rodents using a liposomal, nanoparticle contrast agent.
Publication
, Journal Article
Samei, E; Saunders, RS; Badea, CT; Ghaghada, KB; Hedlund, LW; Qi, Y; Yuan, H; Bentley, RC; Mukundan, S
Published in: Int J Nanomedicine
2009
A long circulating liposomal, nanoscale blood pool agent encapsulating traditional iodinated contrast agent (65 mg I/mL) was used for micro-computed tomography (CT) imaging of rats implanted with R3230AC mammary carcinoma. Three-dimensional vascular architecture of tumors was imaged at 100-micron isotropic resolution. The image data showed good qualitative correlation with pathologic findings. The approach holds promise for studying tumor angiogenesis and for evaluating anti-angiogenesis therapies.
Duke Scholars
Published In
Int J Nanomedicine
EISSN
1178-2013
Publication Date
2009
Volume
4
Start / End Page
277 / 282
Location
New Zealand
Related Subject Headings
- Tomography, X-Ray Computed
- Rats, Inbred F344
- Rats
- Radiographic Image Enhancement
- Nanoscience & Nanotechnology
- Nanoparticles
- Mammography
- Mammary Neoplasms, Animal
- Liposomes
- Iopamidol
Citation
APA
Chicago
ICMJE
MLA
NLM
Samei, E., Saunders, R. S., Badea, C. T., Ghaghada, K. B., Hedlund, L. W., Qi, Y., … Mukundan, S. (2009). Micro-CT imaging of breast tumors in rodents using a liposomal, nanoparticle contrast agent. Int J Nanomedicine, 4, 277–282.
Samei, Ehsan, Robert S. Saunders, Cristian T. Badea, Ketan B. Ghaghada, Laurence W. Hedlund, Yi Qi, Hong Yuan, Rex C. Bentley, and Srinivasan Mukundan. “Micro-CT imaging of breast tumors in rodents using a liposomal, nanoparticle contrast agent.” Int J Nanomedicine 4 (2009): 277–82.
Samei E, Saunders RS, Badea CT, Ghaghada KB, Hedlund LW, Qi Y, et al. Micro-CT imaging of breast tumors in rodents using a liposomal, nanoparticle contrast agent. Int J Nanomedicine. 2009;4:277–82.
Samei, Ehsan, et al. “Micro-CT imaging of breast tumors in rodents using a liposomal, nanoparticle contrast agent.” Int J Nanomedicine, vol. 4, 2009, pp. 277–82.
Samei E, Saunders RS, Badea CT, Ghaghada KB, Hedlund LW, Qi Y, Yuan H, Bentley RC, Mukundan S. Micro-CT imaging of breast tumors in rodents using a liposomal, nanoparticle contrast agent. Int J Nanomedicine. 2009;4:277–282.
Published In
Int J Nanomedicine
EISSN
1178-2013
Publication Date
2009
Volume
4
Start / End Page
277 / 282
Location
New Zealand
Related Subject Headings
- Tomography, X-Ray Computed
- Rats, Inbred F344
- Rats
- Radiographic Image Enhancement
- Nanoscience & Nanotechnology
- Nanoparticles
- Mammography
- Mammary Neoplasms, Animal
- Liposomes
- Iopamidol