Identification of 3-hydroxy-2-(3-hydroxyphenyl)-4H-1-benzopyran-4-ones as isoform-selective PKC-zeta inhibitors and potential therapeutics for psychostimulant abuse.
Publication
, Journal Article
Yuan, L; Seo, J-S; Kang, NS; Keinan, S; Steele, SE; Michelotti, GA; Wetsel, WC; Beratan, DN; Gong, Y-D; Lee, TH; Hong, J
Published in: Mol Biosyst
September 2009
From a screen of small molecule libraries to identify potential therapeutics for psychostimulant abuse, 3-hydroxy-2-(3-hydroxyphenyl)-4H-1-benzopyran-4-ones were shown to be isoform-selective PKC-zeta inhibitors.
Duke Scholars
Published In
Mol Biosyst
DOI
EISSN
1742-2051
Publication Date
September 2009
Volume
5
Issue
9
Start / End Page
927 / 930
Location
England
Related Subject Headings
- Substrate Specificity
- Small Molecule Libraries
- Protein Kinase Inhibitors
- Protein Kinase C
- Protein Isoforms
- Models, Molecular
- Kinetics
- Flavonoids
- Chlorocebus aethiops
- COS Cells
Citation
APA
Chicago
ICMJE
MLA
NLM
Yuan, L., Seo, J.-S., Kang, N. S., Keinan, S., Steele, S. E., Michelotti, G. A., … Hong, J. (2009). Identification of 3-hydroxy-2-(3-hydroxyphenyl)-4H-1-benzopyran-4-ones as isoform-selective PKC-zeta inhibitors and potential therapeutics for psychostimulant abuse. Mol Biosyst, 5(9), 927–930. https://doi.org/10.1039/b903036k
Yuan, Langtian, Jin-Soo Seo, Nam Sook Kang, Shahar Keinan, Sarah E. Steele, Gregory A. Michelotti, William C. Wetsel, et al. “Identification of 3-hydroxy-2-(3-hydroxyphenyl)-4H-1-benzopyran-4-ones as isoform-selective PKC-zeta inhibitors and potential therapeutics for psychostimulant abuse.” Mol Biosyst 5, no. 9 (September 2009): 927–30. https://doi.org/10.1039/b903036k.
Yuan L, Seo J-S, Kang NS, Keinan S, Steele SE, Michelotti GA, et al. Identification of 3-hydroxy-2-(3-hydroxyphenyl)-4H-1-benzopyran-4-ones as isoform-selective PKC-zeta inhibitors and potential therapeutics for psychostimulant abuse. Mol Biosyst. 2009 Sep;5(9):927–30.
Yuan, Langtian, et al. “Identification of 3-hydroxy-2-(3-hydroxyphenyl)-4H-1-benzopyran-4-ones as isoform-selective PKC-zeta inhibitors and potential therapeutics for psychostimulant abuse.” Mol Biosyst, vol. 5, no. 9, Sept. 2009, pp. 927–30. Pubmed, doi:10.1039/b903036k.
Yuan L, Seo J-S, Kang NS, Keinan S, Steele SE, Michelotti GA, Wetsel WC, Beratan DN, Gong Y-D, Lee TH, Hong J. Identification of 3-hydroxy-2-(3-hydroxyphenyl)-4H-1-benzopyran-4-ones as isoform-selective PKC-zeta inhibitors and potential therapeutics for psychostimulant abuse. Mol Biosyst. 2009 Sep;5(9):927–930.
Published In
Mol Biosyst
DOI
EISSN
1742-2051
Publication Date
September 2009
Volume
5
Issue
9
Start / End Page
927 / 930
Location
England
Related Subject Headings
- Substrate Specificity
- Small Molecule Libraries
- Protein Kinase Inhibitors
- Protein Kinase C
- Protein Isoforms
- Models, Molecular
- Kinetics
- Flavonoids
- Chlorocebus aethiops
- COS Cells