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Digital tomosynthesis with an on-board kilovoltage imaging device.

Publication ,  Journal Article
Godfrey, DJ; Yin, F-F; Oldham, M; Yoo, S; Willett, C
Published in: Int J Radiat Oncol Biol Phys
May 1, 2006

PURPOSE: To generate on-board digital tomosynthesis (DTS) and reference DTS images for three-dimensional image-guided radiation therapy (IGRT) as an alternative to conventional portal imaging or on-board cone-beam computed tomography (CBCT). METHODS AND MATERIALS: Three clinical cases (prostate, head-and-neck, and liver) were selected to illustrate the capabilities of on-board DTS for IGRT. Corresponding reference DTS images were reconstructed from digitally reconstructed radiographs computed from planning CT image sets. The effect of scan angle on DTS slice thickness was examined by computing the mutual information between coincident CBCT and DTS images, as the DTS scan angle was varied from 0 degrees to 165 degrees . A breath-hold DTS acquisition strategy was implemented to remove respiratory motion artifacts. RESULTS: Digital tomosynthesis slices appeared similar to coincident CBCT planes and yielded substantially more anatomic information than either kilovoltage or megavoltage radiographs. Breath-hold DTS acquisition improved soft-tissue visibility by suppressing respiratory motion. CONCLUSIONS: Improved bony and soft-tissue visibility in DTS images is likely to improve target localization compared with radiographic verification techniques and might allow for daily localization of a soft-tissue target. Breath-hold DTS is a potential alternative to on-board CBCT for sites prone to respiratory motion.

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Published In

Int J Radiat Oncol Biol Phys

DOI

ISSN

0360-3016

Publication Date

May 1, 2006

Volume

65

Issue

1

Start / End Page

8 / 15

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Radiographic Image Interpretation, Computer-Assisted
  • Prostatic Neoplasms
  • Oncology & Carcinogenesis
  • Neoplasms
  • Male
  • Liver Neoplasms
  • Imaging, Three-Dimensional
  • Humans
  • Head and Neck Neoplasms
 

Citation

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Godfrey, D. J., Yin, F.-F., Oldham, M., Yoo, S., & Willett, C. (2006). Digital tomosynthesis with an on-board kilovoltage imaging device. Int J Radiat Oncol Biol Phys, 65(1), 8–15. https://doi.org/10.1016/j.ijrobp.2006.01.025
Godfrey, Devon J., Fang-Fang Yin, Mark Oldham, Sua Yoo, and Christopher Willett. “Digital tomosynthesis with an on-board kilovoltage imaging device.Int J Radiat Oncol Biol Phys 65, no. 1 (May 1, 2006): 8–15. https://doi.org/10.1016/j.ijrobp.2006.01.025.
Godfrey DJ, Yin F-F, Oldham M, Yoo S, Willett C. Digital tomosynthesis with an on-board kilovoltage imaging device. Int J Radiat Oncol Biol Phys. 2006 May 1;65(1):8–15.
Godfrey, Devon J., et al. “Digital tomosynthesis with an on-board kilovoltage imaging device.Int J Radiat Oncol Biol Phys, vol. 65, no. 1, May 2006, pp. 8–15. Pubmed, doi:10.1016/j.ijrobp.2006.01.025.
Godfrey DJ, Yin F-F, Oldham M, Yoo S, Willett C. Digital tomosynthesis with an on-board kilovoltage imaging device. Int J Radiat Oncol Biol Phys. 2006 May 1;65(1):8–15.

Published In

Int J Radiat Oncol Biol Phys

DOI

ISSN

0360-3016

Publication Date

May 1, 2006

Volume

65

Issue

1

Start / End Page

8 / 15

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Radiographic Image Interpretation, Computer-Assisted
  • Prostatic Neoplasms
  • Oncology & Carcinogenesis
  • Neoplasms
  • Male
  • Liver Neoplasms
  • Imaging, Three-Dimensional
  • Humans
  • Head and Neck Neoplasms