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Economic evaluation of the HF-ACTION (Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Training) randomized controlled trial: an exercise training study of patients with chronic heart failure.

Publication ,  Journal Article
Reed, SD; Whellan, DJ; Li, Y; Friedman, JY; Ellis, SJ; Piña, IL; Settles, SJ; Davidson-Ray, L; Johnson, JL; Cooper, LS; O'Connor, CM ...
Published in: Circ Cardiovasc Qual Outcomes
July 2010

BACKGROUND: Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION) assigned 2331 outpatients with medically stable heart failure to exercise training or usual care. We compared medical resource use and costs incurred by these patients during follow-up. METHODS AND RESULTS: Extensive data on medical resource use and hospital bills were collected throughout the trial for estimates of direct medical costs. Intervention costs were estimated using patient-level trial data, administrative records, and published unit costs. Mean follow-up was 2.5 years. There were 2297 hospitalizations in the exercise group and 2332 in the usual care group (P=0.92). The mean number of inpatient days was 13.6 (standard deviation [SD], 27.0) in the exercise group and 15.0 (SD, 31.4) in the usual care group (P=0.23). Other measures of resource use were similar between groups, except for trends indicating that fewer patients in the exercise group underwent high-cost inpatient procedures. Total direct medical costs per participant were an estimated $50,857 (SD, $81,488) in the exercise group and $56,177 (SD, $92,749) in the usual care group (95% confidence interval for the difference, $-12,755 to $1547; P=0.10). The direct cost of exercise training was an estimated $1006 (SD, $337). Patient time costs were an estimated $5018 (SD, $4600). CONCLUSIONS: The cost of exercise training was relatively low for the health care system, but patients incurred significant time costs. In this economic evaluation, there was little systematic benefit in terms of overall medical resource use with this intervention. CLINICAL TRIAL REGISTRATION: URL: http://www.clinicaltrials.gov. Unique identifier: NCT00047437.

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Published In

Circ Cardiovasc Qual Outcomes

DOI

EISSN

1941-7705

Publication Date

July 2010

Volume

3

Issue

4

Start / End Page

374 / 381

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Middle Aged
  • Male
  • Humans
  • Hospitalization
  • Heart Failure
  • Health Care Costs
  • Follow-Up Studies
  • Female
  • Exercise Therapy
 

Citation

APA
Chicago
ICMJE
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Reed, S. D., Whellan, D. J., Li, Y., Friedman, J. Y., Ellis, S. J., Piña, I. L., … HF-ACTION Investigators, . (2010). Economic evaluation of the HF-ACTION (Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Training) randomized controlled trial: an exercise training study of patients with chronic heart failure. Circ Cardiovasc Qual Outcomes, 3(4), 374–381. https://doi.org/10.1161/CIRCOUTCOMES.109.907287
Reed, Shelby D., David J. Whellan, Yanhong Li, Joëlle Y. Friedman, Stephen J. Ellis, Ileana L. Piña, Sharon J. Settles, et al. “Economic evaluation of the HF-ACTION (Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Training) randomized controlled trial: an exercise training study of patients with chronic heart failure.Circ Cardiovasc Qual Outcomes 3, no. 4 (July 2010): 374–81. https://doi.org/10.1161/CIRCOUTCOMES.109.907287.
Reed, Shelby D., et al. “Economic evaluation of the HF-ACTION (Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Training) randomized controlled trial: an exercise training study of patients with chronic heart failure.Circ Cardiovasc Qual Outcomes, vol. 3, no. 4, July 2010, pp. 374–81. Pubmed, doi:10.1161/CIRCOUTCOMES.109.907287.
Reed SD, Whellan DJ, Li Y, Friedman JY, Ellis SJ, Piña IL, Settles SJ, Davidson-Ray L, Johnson JL, Cooper LS, O’Connor CM, Schulman KA, HF-ACTION Investigators. Economic evaluation of the HF-ACTION (Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Training) randomized controlled trial: an exercise training study of patients with chronic heart failure. Circ Cardiovasc Qual Outcomes. 2010 Jul;3(4):374–381.

Published In

Circ Cardiovasc Qual Outcomes

DOI

EISSN

1941-7705

Publication Date

July 2010

Volume

3

Issue

4

Start / End Page

374 / 381

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Middle Aged
  • Male
  • Humans
  • Hospitalization
  • Heart Failure
  • Health Care Costs
  • Follow-Up Studies
  • Female
  • Exercise Therapy