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Impact of saphenous vein graft radiographic markers on clinical events and angiographic parameters.

Publication ,  Journal Article
Olenchock, SA; Karmpaliotis, D; Gibson, WJ; Murphy, SA; Southard, MC; Ciaglo, L; Buros, J; Mack, MJ; Alexander, JH; Harrington, RA; Califf, RM ...
Published in: Ann Thorac Surg
February 2008

BACKGROUND: Use of saphenous vein graft (SVG) radiographic markers has been associated with shorter cardiac catheterization procedure times and reduced contrast agent volume for postoperative coronary artery bypass graft (CABG) catheterizations. Use of such markers is varied and often operator-dependent, as the effect of SVG markers has not been fully evaluated. The goal of the present analysis was to evaluate the association of SVG markers with clinical outcomes and graft patency. METHODS: Data were drawn from the Project of Ex-vivo Vein Graft Engineering via Transfection (PREVENT) IV trial of patients undergoing CABG at 107 hospitals across the United States. Repeat angiography was performed within 12 to 18 months after CABG. The SVG markers were used at the discretion of the surgeon and were identified on the follow-up angiogram as any device used to mark the ostium, regardless of shape. RESULTS: The SVG markers were present in 51.2% of evaluable patients (910 of 1,778) and 52.3% of SVGs (2,228 of 4,240). Among patients with totally occluded SVGs (n = 911), visual identification of the SVG was obtained more frequently in those with an SVG marker (90.7% vs 72.1%, p < 0.001). The SVG stenosis 70% or greater at follow-up did not differ by use of markers (25.8% with marker vs 24.4% without marker, p = not significant). These findings were also consistent in ostial lesions (n = 942). Long-term death or myocardial infarction (MI) was similar by use of marker. The perioperative CABG MI was higher in patients with SVG markers (10.1% vs 5.5%, odds ratio adjusted 1.86, p = 0.021). CONCLUSIONS: Saphenous vein graft radiographic markers were associated with higher rates of direct visualization of totally occluded SVGs without an adverse effect on graft patency or long-term clinical outcomes, but the association of SVG markers with increased perioperative CABG MI warrants further examination.

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Published In

Ann Thorac Surg

DOI

EISSN

1552-6259

Publication Date

February 2008

Volume

85

Issue

2

Start / End Page

520 / 524

Location

Netherlands

Related Subject Headings

  • Vascular Patency
  • Survival Rate
  • Sex Distribution
  • Sensitivity and Specificity
  • Saphenous Vein
  • Risk Assessment
  • Respiratory System
  • Reference Values
  • Prospective Studies
  • Middle Aged
 

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Olenchock, S. A., Karmpaliotis, D., Gibson, W. J., Murphy, S. A., Southard, M. C., Ciaglo, L., … Gibson, C. M. (2008). Impact of saphenous vein graft radiographic markers on clinical events and angiographic parameters. Ann Thorac Surg, 85(2), 520–524. https://doi.org/10.1016/j.athoracsur.2007.10.061
Olenchock, Stephen A., Dimitri Karmpaliotis, William J. Gibson, Sabina A. Murphy, Matthew C. Southard, Lauren Ciaglo, Jacqueline Buros, et al. “Impact of saphenous vein graft radiographic markers on clinical events and angiographic parameters.Ann Thorac Surg 85, no. 2 (February 2008): 520–24. https://doi.org/10.1016/j.athoracsur.2007.10.061.
Olenchock SA, Karmpaliotis D, Gibson WJ, Murphy SA, Southard MC, Ciaglo L, et al. Impact of saphenous vein graft radiographic markers on clinical events and angiographic parameters. Ann Thorac Surg. 2008 Feb;85(2):520–4.
Olenchock, Stephen A., et al. “Impact of saphenous vein graft radiographic markers on clinical events and angiographic parameters.Ann Thorac Surg, vol. 85, no. 2, Feb. 2008, pp. 520–24. Pubmed, doi:10.1016/j.athoracsur.2007.10.061.
Olenchock SA, Karmpaliotis D, Gibson WJ, Murphy SA, Southard MC, Ciaglo L, Buros J, Mack MJ, Alexander JH, Harrington RA, Califf RM, Kouchoukos NT, Ferguson TB, Gibson CM. Impact of saphenous vein graft radiographic markers on clinical events and angiographic parameters. Ann Thorac Surg. 2008 Feb;85(2):520–524.
Journal cover image

Published In

Ann Thorac Surg

DOI

EISSN

1552-6259

Publication Date

February 2008

Volume

85

Issue

2

Start / End Page

520 / 524

Location

Netherlands

Related Subject Headings

  • Vascular Patency
  • Survival Rate
  • Sex Distribution
  • Sensitivity and Specificity
  • Saphenous Vein
  • Risk Assessment
  • Respiratory System
  • Reference Values
  • Prospective Studies
  • Middle Aged