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Intracranial dual-mode IVUS and hyperthermia using circular arrays

Publication ,  Conference
Patel, V; Light, E; Herickhoff, C; Palmeri, M; Grant, G; Britz, G; Wilson, C; Smith, S
Published in: IEEE International Ultrasonics Symposium, IUS
December 1, 2011

In this study, we investigated the feasibility of using 3.5-Fr circular phased array IVUS catheters for minimally invasive, image-guided hyperthermia treatment of tumors in the brain. Feasibility was demonstrated in two ways: 1) by fitting a 3.5-Fr IVUS catheter through burr holes, for 20 MHz imaging, and 2) by testing a modified circular array for therapy potential with 18.5-MHz and 9.0 MHz CW excitation. The imaging transducer's performance was compared to our previous 9 MHz mechanical IVUS prototype. The therapy transducer was driven by CW electrical power, achieving temperature changes reaching +8°C at a depth of 2 mm in human glioblastoma tissue grown on the flank of a mouse. Further hyperthermia trials showed that resistive heating of the transducer was minimal producing a +2°C increase with CW excitation. © 2011 IEEE.

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Published In

IEEE International Ultrasonics Symposium, IUS

DOI

EISSN

1948-5727

ISSN

1948-5719

Publication Date

December 1, 2011

Start / End Page

2185 / 2188
 

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Patel, V., Light, E., Herickhoff, C., Palmeri, M., Grant, G., Britz, G., … Smith, S. (2011). Intracranial dual-mode IVUS and hyperthermia using circular arrays. In IEEE International Ultrasonics Symposium, IUS (pp. 2185–2188). https://doi.org/10.1109/ULTSYM.2011.0542
Patel, V., E. Light, C. Herickhoff, M. Palmeri, G. Grant, G. Britz, C. Wilson, and S. Smith. “Intracranial dual-mode IVUS and hyperthermia using circular arrays.” In IEEE International Ultrasonics Symposium, IUS, 2185–88, 2011. https://doi.org/10.1109/ULTSYM.2011.0542.
Patel V, Light E, Herickhoff C, Palmeri M, Grant G, Britz G, et al. Intracranial dual-mode IVUS and hyperthermia using circular arrays. In: IEEE International Ultrasonics Symposium, IUS. 2011. p. 2185–8.
Patel, V., et al. “Intracranial dual-mode IVUS and hyperthermia using circular arrays.” IEEE International Ultrasonics Symposium, IUS, 2011, pp. 2185–88. Scopus, doi:10.1109/ULTSYM.2011.0542.
Patel V, Light E, Herickhoff C, Palmeri M, Grant G, Britz G, Wilson C, Smith S. Intracranial dual-mode IVUS and hyperthermia using circular arrays. IEEE International Ultrasonics Symposium, IUS. 2011. p. 2185–2188.

Published In

IEEE International Ultrasonics Symposium, IUS

DOI

EISSN

1948-5727

ISSN

1948-5719

Publication Date

December 1, 2011

Start / End Page

2185 / 2188