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Dual-mode IVUS catheter for intracranial image-guided hyperthermia: feasibility study.

Publication ,  Journal Article
Herickhoff, CD; Grant, GA; Britz, GW; Smith, SW
Published in: IEEE Trans Ultrason Ferroelectr Freq Control
November 2010

In this study, we investigated the feasibility of modifying 3-Fr IVUS catheters in several designs to potentially achieve minimally-invasive, endovascular access for image-guided ultrasound hyperthermia treatment of tumors in the brain. Using a plane wave approximation, target frequencies of 8.7 and 3.5 MHz were considered optimal for heating at depths (tumor sizes) of 1 and 2.5 cm, respectively. First, a 3.5-Fr IVUS catheter with a 0.7-mm diameter transducer (30 MHz nominal frequency) was driven at 8.6 MHz. Second, for a low-frequency design, a 220-μm-thick, 0.35 x 0.35-mm PZT-4 transducer--driven at width-mode resonance of 3.85 MHz--replaced a 40-MHz element in a 3.5-Fr coronary imaging catheter. Third, a 5 x 0.5-mm PZT-4 transducer was evaluated as the largest aperture geometry possible for a flexible 3-Fr IVUS catheter. Beam plots and on-axis heating profiles were simulated for each aperture, and test transducers were fabricated. The electrical impedance, impulse response, frequency response, maximum intensity, and mechanical index were measured to assess performance. For the 5 x 0.5-mm transducer, this testing also included mechanically scanning and reconstructing an image of a 2.5-cm-diameter cyst phantom as a preliminary measure of imaging potential.

Duke Scholars

Published In

IEEE Trans Ultrason Ferroelectr Freq Control

DOI

EISSN

1525-8955

Publication Date

November 2010

Volume

57

Issue

11

Start / End Page

2572 / 2584

Location

United States

Related Subject Headings

  • Ultrasonography, Interventional
  • Transducers
  • Surgery, Computer-Assisted
  • Phantoms, Imaging
  • Models, Theoretical
  • Hyperthermia, Induced
  • Humans
  • Feasibility Studies
  • Equipment Design
  • Cysts
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Herickhoff, C. D., Grant, G. A., Britz, G. W., & Smith, S. W. (2010). Dual-mode IVUS catheter for intracranial image-guided hyperthermia: feasibility study. IEEE Trans Ultrason Ferroelectr Freq Control, 57(11), 2572–2584. https://doi.org/10.1109/TUFFC.2010.1723
Herickhoff, Carl D., Gerald A. Grant, Gavin W. Britz, and Stephen W. Smith. “Dual-mode IVUS catheter for intracranial image-guided hyperthermia: feasibility study.IEEE Trans Ultrason Ferroelectr Freq Control 57, no. 11 (November 2010): 2572–84. https://doi.org/10.1109/TUFFC.2010.1723.
Herickhoff CD, Grant GA, Britz GW, Smith SW. Dual-mode IVUS catheter for intracranial image-guided hyperthermia: feasibility study. IEEE Trans Ultrason Ferroelectr Freq Control. 2010 Nov;57(11):2572–84.
Herickhoff, Carl D., et al. “Dual-mode IVUS catheter for intracranial image-guided hyperthermia: feasibility study.IEEE Trans Ultrason Ferroelectr Freq Control, vol. 57, no. 11, Nov. 2010, pp. 2572–84. Pubmed, doi:10.1109/TUFFC.2010.1723.
Herickhoff CD, Grant GA, Britz GW, Smith SW. Dual-mode IVUS catheter for intracranial image-guided hyperthermia: feasibility study. IEEE Trans Ultrason Ferroelectr Freq Control. 2010 Nov;57(11):2572–2584.

Published In

IEEE Trans Ultrason Ferroelectr Freq Control

DOI

EISSN

1525-8955

Publication Date

November 2010

Volume

57

Issue

11

Start / End Page

2572 / 2584

Location

United States

Related Subject Headings

  • Ultrasonography, Interventional
  • Transducers
  • Surgery, Computer-Assisted
  • Phantoms, Imaging
  • Models, Theoretical
  • Hyperthermia, Induced
  • Humans
  • Feasibility Studies
  • Equipment Design
  • Cysts