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Administration of thrombolytic therapy in the community hospital: established principles and unresolved issues.

Publication ,  Journal Article
Mark, DB; Hlatky, MA; O'Connor, CM; Pryor, DB; Wall, TC; Honan, MB; Phillips, HR; Califf, RM
Published in: J Am Coll Cardiol
December 1988

In patients with acute myocardial infarction presenting to community hospitals, thrombolytic therapy should be initiated as rapidly as possible under the supervision of a physician. Paramedic or nurse-initiated pre-hospital therapy is currently investigational. Each hospital must have a detailed evaluation and treatment protocol for acute myocardial infarction that specifies the timetable for patient evaluation, who should or should not receive thrombolytic therapy and the proper dose and mode of administration of the agent or agents to be used. Monitoring after the administration of thrombolytic therapy should focus on arrhythmias, hemodynamic problems, recurrent ischemia and bleeding. The role of early cardiac catheterization to detect patients who have unsuccessful thrombolysis or who require mechanical revascularization procedures is under active investigation. The design of the Thrombolysis and Angioplasty in Acute Myocardial Infarction (TAMI) 5 study, which addresses the role of acute interventional catheterization in the treatment of patients with acute myocardial infarction, is described.

Duke Scholars

Published In

J Am Coll Cardiol

DOI

ISSN

0735-1097

Publication Date

December 1988

Volume

12

Issue

6 Suppl A

Start / End Page

32A / 43A

Location

United States

Related Subject Headings

  • Time Factors
  • Recurrence
  • Patient Transfer
  • Myocardial Infarction
  • Monitoring, Physiologic
  • Hypotension
  • Humans
  • Hospitals, Community
  • Hemorrhage
  • Fibrinolytic Agents
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Mark, D. B., Hlatky, M. A., O’Connor, C. M., Pryor, D. B., Wall, T. C., Honan, M. B., … Califf, R. M. (1988). Administration of thrombolytic therapy in the community hospital: established principles and unresolved issues. J Am Coll Cardiol, 12(6 Suppl A), 32A-43A. https://doi.org/10.1016/0735-1097(88)92639-3
Mark, D. B., M. A. Hlatky, C. M. O’Connor, D. B. Pryor, T. C. Wall, M. B. Honan, H. R. Phillips, and R. M. Califf. “Administration of thrombolytic therapy in the community hospital: established principles and unresolved issues.J Am Coll Cardiol 12, no. 6 Suppl A (December 1988): 32A-43A. https://doi.org/10.1016/0735-1097(88)92639-3.
Mark DB, Hlatky MA, O’Connor CM, Pryor DB, Wall TC, Honan MB, et al. Administration of thrombolytic therapy in the community hospital: established principles and unresolved issues. J Am Coll Cardiol. 1988 Dec;12(6 Suppl A):32A-43A.
Mark, D. B., et al. “Administration of thrombolytic therapy in the community hospital: established principles and unresolved issues.J Am Coll Cardiol, vol. 12, no. 6 Suppl A, Dec. 1988, pp. 32A-43A. Pubmed, doi:10.1016/0735-1097(88)92639-3.
Mark DB, Hlatky MA, O’Connor CM, Pryor DB, Wall TC, Honan MB, Phillips HR, Califf RM. Administration of thrombolytic therapy in the community hospital: established principles and unresolved issues. J Am Coll Cardiol. 1988 Dec;12(6 Suppl A):32A-43A.
Journal cover image

Published In

J Am Coll Cardiol

DOI

ISSN

0735-1097

Publication Date

December 1988

Volume

12

Issue

6 Suppl A

Start / End Page

32A / 43A

Location

United States

Related Subject Headings

  • Time Factors
  • Recurrence
  • Patient Transfer
  • Myocardial Infarction
  • Monitoring, Physiologic
  • Hypotension
  • Humans
  • Hospitals, Community
  • Hemorrhage
  • Fibrinolytic Agents