
High-resolution in vivo imaging of blood vessels without labeling.
Publication
, Journal Article
Fu, D; Ye, T; Matthews, TE; Chen, BJ; Yurtserver, G; Warren, WS
Published in: Opt Lett
September 15, 2007
We demonstrate that both oxyhemoglobin and deoxyhemoglobin have sequential two-color, two-photon absorption properties that can serve as endogenous contrasts in microvasculature imaging. Using a sensitive modulation transfer technique, we are able to image hemoglobin in red blood cells with micrometer resolution, both in vitro and in vivo. We show that excellent contrast from hemoglobin without any labeling can be obtained in tissue.
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Published In
Opt Lett
DOI
ISSN
0146-9592
Publication Date
September 15, 2007
Volume
32
Issue
18
Start / End Page
2641 / 2643
Location
United States
Related Subject Headings
- Staining and Labeling
- Optics
- Microscopy, Fluorescence, Multiphoton
- Mice
- Hemoglobins
- Erythrocytes
- Cells, Cultured
- Blood Vessels
- Animals
- 5102 Atomic, molecular and optical physics
Citation
APA
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ICMJE
MLA
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Fu, D., Ye, T., Matthews, T. E., Chen, B. J., Yurtserver, G., & Warren, W. S. (2007). High-resolution in vivo imaging of blood vessels without labeling. Opt Lett, 32(18), 2641–2643. https://doi.org/10.1364/ol.32.002641
Fu, Dan, Tong Ye, Thomas E. Matthews, Benny J. Chen, Gunay Yurtserver, and Warren S. Warren. “High-resolution in vivo imaging of blood vessels without labeling.” Opt Lett 32, no. 18 (September 15, 2007): 2641–43. https://doi.org/10.1364/ol.32.002641.
Fu D, Ye T, Matthews TE, Chen BJ, Yurtserver G, Warren WS. High-resolution in vivo imaging of blood vessels without labeling. Opt Lett. 2007 Sep 15;32(18):2641–3.
Fu, Dan, et al. “High-resolution in vivo imaging of blood vessels without labeling.” Opt Lett, vol. 32, no. 18, Sept. 2007, pp. 2641–43. Pubmed, doi:10.1364/ol.32.002641.
Fu D, Ye T, Matthews TE, Chen BJ, Yurtserver G, Warren WS. High-resolution in vivo imaging of blood vessels without labeling. Opt Lett. 2007 Sep 15;32(18):2641–2643.

Published In
Opt Lett
DOI
ISSN
0146-9592
Publication Date
September 15, 2007
Volume
32
Issue
18
Start / End Page
2641 / 2643
Location
United States
Related Subject Headings
- Staining and Labeling
- Optics
- Microscopy, Fluorescence, Multiphoton
- Mice
- Hemoglobins
- Erythrocytes
- Cells, Cultured
- Blood Vessels
- Animals
- 5102 Atomic, molecular and optical physics