Primary intracerebral Hodgkin lymphoma with recurrence.
OBJECTIVE: To report a case of primary intracerebral Hodgkin lymphoma with disease recurrence. METHODS: Case report and review of the literature. RESULTS: A 58-year-old immunocompetent male presented with aphasia. Neuroimaging revealed a left temporal lobe lesion. A craniotomy and resection were performed, and the diagnosis of classical Hodgkin lymphoma was made. Systemic work-up for lymphoma was negative. Postoperatively, the patient was treated with whole brain irradiation. 14 months later, the patient developed an enhancing lesion in his pons and received combination chemotherapy and radiation therapy. Repeat imaging demonstrated leptomeningeal enhancement and multiple lesions throughout the cerebral hemispheres, cerebellum and brainstem. COMMENT: We report what appears to be the first case of a patient with aggressive primary intracerebral Hodgkin lymphoma with disease recurrence.
Duke Scholars
Published In
DOI
ISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- Neurosurgical Procedures
- Neurology & Neurosurgery
- Neoplasm Recurrence, Local
- Middle Aged
- Male
- Humans
- Hodgkin Disease
- Fatal Outcome
- Cranial Irradiation
- Brain Neoplasms
Citation
Published In
DOI
ISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- Neurosurgical Procedures
- Neurology & Neurosurgery
- Neoplasm Recurrence, Local
- Middle Aged
- Male
- Humans
- Hodgkin Disease
- Fatal Outcome
- Cranial Irradiation
- Brain Neoplasms