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Existence of bistability and correlation with arrhythmogenesis in sheep atria

Publication ,  Journal Article
Oliver, RA; Krassowska, W; Hall, GM; Bahar, S; Wolf, PD; Gauthier, DJ
Published in: Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
December 1, 1999

This experimental study investigates the response of sheep atria to periodic pacing. In 23 trials over 6 animals, a window of bistability was observed wherein for a range of pacing periods the atria responded 1:1 or 2:1 depending on whether pacing period was increasing or decreasing. In 18 trials, non-paced activations were also observed. In 17 of those 18 trials, the non-paced activations occurred at pacing periods within or no more than 30 ms away from the window of bistability. These results suggest bistability exists in cardiac tissue and is correlated with arrhythmogenesis.

Duke Scholars

Published In

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings

ISSN

0589-1019

Publication Date

December 1, 1999

Volume

1

Start / End Page

157
 

Citation

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Oliver, R. A., Krassowska, W., Hall, G. M., Bahar, S., Wolf, P. D., & Gauthier, D. J. (1999). Existence of bistability and correlation with arrhythmogenesis in sheep atria. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings, 1, 157.
Oliver, R. A., W. Krassowska, G. M. Hall, S. Bahar, P. D. Wolf, and D. J. Gauthier. “Existence of bistability and correlation with arrhythmogenesis in sheep atria.” Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings 1 (December 1, 1999): 157.
Oliver RA, Krassowska W, Hall GM, Bahar S, Wolf PD, Gauthier DJ. Existence of bistability and correlation with arrhythmogenesis in sheep atria. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 1999 Dec 1;1:157.
Oliver, R. A., et al. “Existence of bistability and correlation with arrhythmogenesis in sheep atria.” Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings, vol. 1, Dec. 1999, p. 157.
Oliver RA, Krassowska W, Hall GM, Bahar S, Wolf PD, Gauthier DJ. Existence of bistability and correlation with arrhythmogenesis in sheep atria. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 1999 Dec 1;1:157.

Published In

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings

ISSN

0589-1019

Publication Date

December 1, 1999

Volume

1

Start / End Page

157