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Microwave treatment of intracerebral L1210 leukemia: schedule-dependent partial reversal of the effects of methotrexate.

Publication ,  Journal Article
Chang, BK; Huang, AT; Joines, WT
Published in: Bioelectromagnetics
1981

One-GHz microwave (MW) irradiation at a power density of 5 mW/cm2 was combined with methotrexate (MTX) in an attempt to treat more effectively central nervous system (CNS) L1210 leukemia in DBA/2J mice. When mice with CNS leukemia were treated with the combination of MW and MTX, there was no improvement in survival compared with a group of animals treated with MTX alone; however, the group that received MTX before the MW exposure had a significantly reduced survival time compared with the group treated with MTX alone or with the group to which MTX was administered after MW.

Duke Scholars

Published In

Bioelectromagnetics

DOI

ISSN

0197-8462

Publication Date

1981

Volume

2

Issue

1

Start / End Page

77 / 80

Location

United States

Related Subject Headings

  • Neoplasms, Experimental
  • Microwaves
  • Mice, Inbred DBA
  • Mice
  • Methotrexate
  • Male
  • Leukemia L1210
  • Brain Neoplasms
  • Biophysics
  • Animals
 

Citation

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Chicago
ICMJE
MLA
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Chang, B. K., Huang, A. T., & Joines, W. T. (1981). Microwave treatment of intracerebral L1210 leukemia: schedule-dependent partial reversal of the effects of methotrexate. Bioelectromagnetics, 2(1), 77–80. https://doi.org/10.1002/bem.2250020109
Chang, B. K., A. T. Huang, and W. T. Joines. “Microwave treatment of intracerebral L1210 leukemia: schedule-dependent partial reversal of the effects of methotrexate.Bioelectromagnetics 2, no. 1 (1981): 77–80. https://doi.org/10.1002/bem.2250020109.
Chang, B. K., et al. “Microwave treatment of intracerebral L1210 leukemia: schedule-dependent partial reversal of the effects of methotrexate.Bioelectromagnetics, vol. 2, no. 1, 1981, pp. 77–80. Pubmed, doi:10.1002/bem.2250020109.
Journal cover image

Published In

Bioelectromagnetics

DOI

ISSN

0197-8462

Publication Date

1981

Volume

2

Issue

1

Start / End Page

77 / 80

Location

United States

Related Subject Headings

  • Neoplasms, Experimental
  • Microwaves
  • Mice, Inbred DBA
  • Mice
  • Methotrexate
  • Male
  • Leukemia L1210
  • Brain Neoplasms
  • Biophysics
  • Animals