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Genomic signatures of diet-related shifts during human origins.

Publication ,  Journal Article
Babbitt, CC; Warner, LR; Fedrigo, O; Wall, CE; Wray, GA
Published in: Proceedings. Biological sciences
April 2011

There are numerous anthropological analyses concerning the importance of diet during human evolution. Diet is thought to have had a profound influence on the human phenotype, and dietary differences have been hypothesized to contribute to the dramatic morphological changes seen in modern humans as compared with non-human primates. Here, we attempt to integrate the results of new genomic studies within this well-developed anthropological context. We then review the current evidence for adaptation related to diet, both at the level of sequence changes and gene expression. Finally, we propose some ways in which new technologies can help identify specific genomic adaptations that have resulted in metabolic and morphological differences between humans and non-human primates.

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Published In

Proceedings. Biological sciences

DOI

EISSN

1471-2954

ISSN

0962-8452

Publication Date

April 2011

Volume

278

Issue

1708

Start / End Page

961 / 969

Related Subject Headings

  • Primates
  • Humans
  • Hominidae
  • Genomics
  • Gene Expression
  • Diet
  • Biological Evolution
  • Base Sequence
  • Animals
  • Adaptation, Physiological
 

Citation

APA
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ICMJE
MLA
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Babbitt, C. C., Warner, L. R., Fedrigo, O., Wall, C. E., & Wray, G. A. (2011). Genomic signatures of diet-related shifts during human origins. Proceedings. Biological Sciences, 278(1708), 961–969. https://doi.org/10.1098/rspb.2010.2433
Babbitt, Courtney C., Lisa R. Warner, Olivier Fedrigo, Christine E. Wall, and Gregory A. Wray. “Genomic signatures of diet-related shifts during human origins.Proceedings. Biological Sciences 278, no. 1708 (April 2011): 961–69. https://doi.org/10.1098/rspb.2010.2433.
Babbitt CC, Warner LR, Fedrigo O, Wall CE, Wray GA. Genomic signatures of diet-related shifts during human origins. Proceedings Biological sciences. 2011 Apr;278(1708):961–9.
Babbitt, Courtney C., et al. “Genomic signatures of diet-related shifts during human origins.Proceedings. Biological Sciences, vol. 278, no. 1708, Apr. 2011, pp. 961–69. Epmc, doi:10.1098/rspb.2010.2433.
Babbitt CC, Warner LR, Fedrigo O, Wall CE, Wray GA. Genomic signatures of diet-related shifts during human origins. Proceedings Biological sciences. 2011 Apr;278(1708):961–969.
Journal cover image

Published In

Proceedings. Biological sciences

DOI

EISSN

1471-2954

ISSN

0962-8452

Publication Date

April 2011

Volume

278

Issue

1708

Start / End Page

961 / 969

Related Subject Headings

  • Primates
  • Humans
  • Hominidae
  • Genomics
  • Gene Expression
  • Diet
  • Biological Evolution
  • Base Sequence
  • Animals
  • Adaptation, Physiological