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Association of anxiety and depression with pulmonary-specific symptoms in chronic obstructive pulmonary disease.

Publication ,  Journal Article
Doyle, T; Palmer, S; Johnson, J; Babyak, MA; Smith, P; Mabe, S; Welty-Wolf, K; Martinu, T; Blumenthal, JA
Published in: Int J Psychiatry Med
2013

OBJECTIVES: To examine the association of anxiety and depression with pulmonary-specific symptoms of Chronic Obstructive Pulmonary Disease (COPD), and to determine the extent to which disease severity and functional capacity modify this association. METHOD: Patients (N = 162) enrolled in the INSPIRE-II study, an ongoing randomized, clinical trial of COPD patients and their caregivers who received either telephone-based coping skills training or education and symptom monitoring. Patients completed a psychosocial test battery including: Brief Fatigue Inventory, St. George's Respiratory Questionnaire, UCSD Shortness of Breath Questionnaire, State-Trait Anxiety Inventory, and Beck Depression Inventory. Measures of disease severity and functional capacity (i.e., FEV1 and six-minute walk test) were also obtained. RESULTS: After covariate adjustment, higher anxiety and depression levels were associated with greater fatigue levels (ps < .001, deltaR2 = 0.16 and 0.29, respectively), shortness of breath (ps < .001, deltaR2 = 0.12 and 0.10), and frequency of COPD symptoms (ps < .001, deltaR2 = 0.11 and 0.13). In addition, functional capacity was a moderator of anxiety and pulmonary-specific COPD symptoms. The association between anxiety and shortness of breath (p = 0.009) and frequency of COPD symptoms (p = 0.02) was greater among patients with lower functional capacity. CONCLUSIONS: Anxiety and depression were associated with higher levels of fatigue, shortness of breath, and frequency of COPD symptoms. It is important for clinicians to be aware of the presence of anxiety and depression in COPD patients, which appears to correlate with pulmonary-specific COPD symptoms, especially in patients with lower functional capacity. Prospective design studies are needed to elucidate the causal relationships between anxiety and depression and pulmonary-specific symptoms in COPD patients.

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Published In

Int J Psychiatry Med

DOI

ISSN

0091-2174

Publication Date

2013

Volume

45

Issue

2

Start / End Page

189 / 202

Location

United States

Related Subject Headings

  • Telephone
  • Surveys and Questionnaires
  • Sick Role
  • Quality of Life
  • Pulmonary Disease, Chronic Obstructive
  • Psychometrics
  • Psychiatry
  • Personality Inventory
  • Patient Education as Topic
  • Middle Aged
 

Citation

APA
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ICMJE
MLA
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Doyle, T., Palmer, S., Johnson, J., Babyak, M. A., Smith, P., Mabe, S., … Blumenthal, J. A. (2013). Association of anxiety and depression with pulmonary-specific symptoms in chronic obstructive pulmonary disease. Int J Psychiatry Med, 45(2), 189–202. https://doi.org/10.2190/PM.45.2.g
Doyle, Todd, Scott Palmer, Julie Johnson, Michael A. Babyak, Patrick Smith, Stephanie Mabe, Karen Welty-Wolf, Tereza Martinu, and James A. Blumenthal. “Association of anxiety and depression with pulmonary-specific symptoms in chronic obstructive pulmonary disease.Int J Psychiatry Med 45, no. 2 (2013): 189–202. https://doi.org/10.2190/PM.45.2.g.
Doyle T, Palmer S, Johnson J, Babyak MA, Smith P, Mabe S, et al. Association of anxiety and depression with pulmonary-specific symptoms in chronic obstructive pulmonary disease. Int J Psychiatry Med. 2013;45(2):189–202.
Doyle, Todd, et al. “Association of anxiety and depression with pulmonary-specific symptoms in chronic obstructive pulmonary disease.Int J Psychiatry Med, vol. 45, no. 2, 2013, pp. 189–202. Pubmed, doi:10.2190/PM.45.2.g.
Doyle T, Palmer S, Johnson J, Babyak MA, Smith P, Mabe S, Welty-Wolf K, Martinu T, Blumenthal JA. Association of anxiety and depression with pulmonary-specific symptoms in chronic obstructive pulmonary disease. Int J Psychiatry Med. 2013;45(2):189–202.

Published In

Int J Psychiatry Med

DOI

ISSN

0091-2174

Publication Date

2013

Volume

45

Issue

2

Start / End Page

189 / 202

Location

United States

Related Subject Headings

  • Telephone
  • Surveys and Questionnaires
  • Sick Role
  • Quality of Life
  • Pulmonary Disease, Chronic Obstructive
  • Psychometrics
  • Psychiatry
  • Personality Inventory
  • Patient Education as Topic
  • Middle Aged