Racially diverse participant registries to facilitate the recruitment of African Americans into presymptomatic Alzheimer's disease studies.

Journal Article (Journal Article)

INTRODUCTION: The Alzheimer's Disease Prevention Registry (ADPR) of the Joseph and Kathleen Bryan Alzheimer's Disease Research Center at Duke University has been successful in achieving a racially diverse and "research ready" cohort of cognitively healthy volunteers. METHODS: The ADPR is based on an infrastructure that includes: (1) an administrative leadership team; (2) a coordinating center; (3) an IT management team; (4) a community engagement team; and (5) collaborations with study partners across disciplines. RESULTS: The ADPR currently has more than 4677 members, 26% of whom are African American. The ADPR has supported 21 studies including 8 biomarker studies, 7 clinical trials, 4 cognitive neuroscience studies, and 2 studies assessing novel computerized measures. DISCUSSION: We describe our experiences establishing and maintaining a diverse ADPR as well as insights on recruitment strategies to increase the representation of African Americans in Alzheimer's disease studies.

Full Text

Duke Authors

Cited Authors

  • Cocroft, S; Welsh-Bohmer, KA; Plassman, BL; Chanti-Ketterl, M; Edmonds, H; Gwyther, L; McCart, M; MacDonald, H; Potter, G; Burke, JR

Published Date

  • August 2020

Published In

Volume / Issue

  • 16 / 8

Start / End Page

  • 1107 - 1114

PubMed ID

  • 32543781

Electronic International Standard Serial Number (EISSN)

  • 1552-5279

Digital Object Identifier (DOI)

  • 10.1002/alz.12048

Language

  • eng

Conference Location

  • United States