Cough in pediatric patients receiving angiotensin-converting enzyme inhibitor therapy or angiotensin receptor blocker therapy in randomized controlled trials.

Journal Article (Journal Article)

The incidence of cough in children receiving antihypertension therapy with angiotensin-converting enzyme inhibitors (ACEis) or angiotensin receptor blockers (ARBs) is unknown. We analyzed patient-level data from eight randomized trials for the treatment of pediatric hypertension, six of them involving ACEis and two involving ARBs. The incidence of cough in children receiving ACEis (reported cough, 3.2%) was similar to that in children receiving ARBs (reported cough, 1.8%) (P = 0.34). Reports of cough were lower in children than in adults.

Full Text

Duke Authors

Cited Authors

  • Baker-Smith, CM; Benjamin, DK; Califf, RM; Murphy, MD; Li, JS; Smith, PB

Published Date

  • June 2010

Published In

Volume / Issue

  • 87 / 6

Start / End Page

  • 668 - 671

PubMed ID

  • 20130570

Pubmed Central ID

  • PMC2874085

Electronic International Standard Serial Number (EISSN)

  • 1532-6535

Digital Object Identifier (DOI)

  • 10.1038/clpt.2009.231


  • eng

Conference Location

  • United States